ChemicalBook > CAS DataBase List > 1-(4-METHYLPHENYL)-1H-PYRROLE-2,5-DIONE

1-(4-METHYLPHENYL)-1H-PYRROLE-2,5-DIONE

Product Name: 1-(4-METHYLPHENYL)-1H-PYRROLE-2,5-DIONE
CAS No.: 1631-28-3
Chemical Name: 1-(4-METHYLPHENYL)-1H-PYRROLE-2,5-DIONE
Synonyms: 1-(p-Tolyl)-1H-pyrrole-2,5-dione;N-(P-TOLYL)MALEIMIDE;IT 510;AKOS B006714;AKOS MSC-0013;ASISCHEM S97813;p-Tolylmaleimide;WLN: T5VNVJ BR D1;n-p-tolyl-maleimid;N-4-Tolylmaleimide
CBNumber: CB9376205
Molecular Formula: C11H9NO2
Formula Weight: 187.19
MOL File: 1631-28-3.mol

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1-(4-METHYLPHENYL)-1H-PYRROLE-2,5-DIONE Property

Melting point:: 149-150 °C
Boiling point:: 333.2±21.0 °C(Predicted)
Density: 1.277±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
form: Solid
pka: -0.29±0.20(Predicted)
color: Light yellow to yellow
CAS DataBase Reference: 1631-28-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S392847
Product name: N-(PARA-TOLYL)-MALEIMIDE
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $185
Updated: 2025/07/31

Sigma-Aldrich

Product number: S392847
Product name: N-(PARA-TOLYL)-MALEIMIDE
Purity: AldrichCPR
Packaging: 50MG
Price: $179
Updated: 2024/03/01

TCI Chemical

Product number: M3573
Product name: 1-(p-Tolyl)-1H-pyrrole-2,5-dione
Purity: min. 98.0 %
Packaging: 200MG
Price: $114
Updated: 2025/07/31

TCI Chemical

Product number: M3573
Product name: 1-(p-Tolyl)-1H-pyrrole-2,5-dione
Purity: min. 98.0 %
Packaging: 1G
Price: $341
Updated: 2025/07/31

TRC

Product number: M220843
Product name: 1-(4-Methylphenyl)-1H-pyrrole-2,5-dione
Packaging: 50mg
Price: $60
Updated: 2021/12/16

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1-(4-METHYLPHENYL)-1H-PYRROLE-2,5-DIONE Chemical Properties,Usage,Production

Uses

p-Tolylmaleimide (compound 9) is a naphthalimide derivative that has cytotoxic effects on cancer cells. p-Tolylmaleimide can arrest the cell cycle of human acute myeloid leukemia cells K562 in the sub-G0/G1 phase and induce apoptosis[1].

References

[1] Machado KE, et al. Apoptotic events induced by maleimides on human acute leukemia cell lines. Chem Res Toxicol. 2013 Dec 16;26(12):1904-16. DOI:10.1021/tx400284r

1-(4-METHYLPHENYL)-1H-PYRROLE-2,5-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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1631-28-3, 1-(4-METHYLPHENYL)-1H-PYRROLE-2,5-DIONERelated Search:

4-(N-Maleimido)benzophenone N-Succinimidyl 4-(4-maleimidophenyl)butyrate Bismaleimide 1-(3-CHLOR-4-METHYLPHENYL)-1H-PYRROLE-2,5-DIONE N-(3-FLUORANTHYL)MALEIMIDE 1-(4-METHYLPHENYL)-1H-PYRROLE-2,5-DIONE N,N'-(4-METHYL-1,3-PHENYLENE)BISMALEIMIDE N-(4-ETHYLPHENYL)MALEIMIDE N-(4-ACETYLPHENYL)MALEIMIDE 7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin FLUORESCEIN-5-MALEIMIDE 1-(3,4-DIMETHYLPHENYL)-1H-PYRROLE-2,5-DIONE 1-(2-METHYLPHENYL)-1H-PYRROLE-2,5-DIONE,N-(O-TOLYL)MALEIMIDE 1-(3-TRIFLUOROMETHYL-PHENYL)-PYRROLE-2,5-DIONE 1-(3-METHYLPHENYL)-1H-PYRROLE-2,5-DIONE 1-(4-METHYLPHENYL)-1 H-PYRROLE N-(4-CARBOXY-3-HYDROXYPHENYL)MALEIMIDE ETHYL 4-(2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-1-YL)BENZOATE

IT 510

Maleimide, N-p-Tolyl-

N-(para-Tolyl)-maleimide

N-(p-Methylphenyl)maleimide

N-4-Tolylmaleimide

n-p-tolyl-maleimid

p-Tolylmaleimide

N-(4-METHYLPHENYL)MALEIMIDE

N-(P-TOLYL)MALEIMIDE

ASISCHEM S97813

ART-CHEM-BB B006714

WLN: T5VNVJ BR D1

AKOS B006714

AKOS MSC-0013

1-(4-METHYLPHENYL)-1H-PYRROLE-2,5-DIONE

1-P-TOLYL-PYRROLE-2,5-DIONE

1-(4-Methylphenyl)-3-pyrroline-2,5-dione

1-p-Tolyl-3-pyrroline-2,5-dione

1-(4-methylphenyl)-3-pyrroline-2,5-quinone

1-(4-methylphenyl)pyrrole-2,5-dione

1H-Pyrrole-2,5-dione, 1-(4-Methylphenyl)-

1-(p-Tolyl)-1H-pyrrole-2,5-dione

1H-Pyrrole-2,5-dione, 1-(4-methylphenyl)- (9CI)

1631-28-3