ChemicalBook > CAS DataBase List > H-PRO-NME2

H-PRO-NME2

Product Name
H-PRO-NME2
CAS No.
29802-22-0
Chemical Name
H-PRO-NME2
Synonyms
N,N-Dimethylpyrrolidine-2-carboxamide;(S)-N,N-dimethylpyrrolidine-2-carboxamide;H-Pro-NMe;L-Pro-NMe2;H-PRO-NME2;PROLINE-NME2;H-PYRD(2)-NME2;H-PRO-NME2 USP/EP/BP;L-PROLINE DIMETHYLAMIDE;L-Proline dimethylamide98%
CBNumber
CB9376553
Molecular Formula
C7H14N2O
Formula Weight
142.2
MOL File
29802-22-0.mol
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H-PRO-NME2 Property

Boiling point:
250.2±29.0 °C(Predicted)
Density 
1.017±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
9.18±0.10(Predicted)
Appearance
Colorless to light yellow Liquid
CAS DataBase Reference
29802-22-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36
Safety Statements 
26
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
P756020
Product name
L-ProlineDimethylamide
Packaging
1g
Price
$120
Updated
2021/12/16
Usbiological
Product number
287818
Product name
L-Proline dimethylamide
Packaging
500mg
Price
$333
Updated
2021/12/16
TRC
Product number
P756020
Product name
L-ProlineDimethylamide
Packaging
5g
Price
$365
Updated
2021/12/16
Chem-Impex
Product number
06200
Product name
L-Prolinedimethylamide,99%(Chiralpurity)
Purity
99%(Chiralpurity)
Packaging
250MG
Price
$33.6
Updated
2021/12/16
Chem-Impex
Product number
06200
Product name
L-Proline dimethylamide
Purity
≥ 99% (Chiral purity)
Packaging
1G
Price
$60
Updated
2021/12/16
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H-PRO-NME2 Chemical Properties,Usage,Production

Uses

L-Proline Dimethylamide is a reactant used in the synthesis of fluoromethylsulfonylaminophenyl propanamides as TRPV1 antagonists.

Synthesis

Take a clean beaker, add 180 mL of tetrahydrofuran solution, weigh and prepare N,N-dimethylpyrrolidine-2-carbonyl chloride dissolved in tetrahydrofuran, after dissolution, the solution was slowly added to the ice-water bath under the conditions of the dimethylamine tetrahydrofuran (which had been loaded into the clean three reaction flasks), the solid was precipitated immediately, and after addition, the stirring was continued for 4 hours at 35 , and the progress of the reaction was detected by thin-layer chromatography. After the reaction was completed and the reaction solution was cooled, 400 mL of ice water was added to the reaction, so that the product was completely precipitated, and a light yellow solid was obtained by filtration. After drying and recrystallization with anhydrous acetone, N,N-dimethylpyrrolidine-2-carboxamide was obtained.

H-PRO-NME2 Preparation Products And Raw materials

Raw materials

Preparation Products

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H-PRO-NME2 Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
Wuhan Haizheng Industry & Trade Development Co. Ltd
Tel
027-8866 0053/88660577/88660578
Fax
027-8899 1911
Country
China
ProdList
1073
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17714375163
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19906
Advantage
55

29802-22-0, H-PRO-NME2Related Search:


  • PROLINE-NME2
  • L-PYRROLIDINE-2-CARBOXYLIC ACID DIMETHYLAMIDE
  • L-PROLINE DIMETHYLAMIDE
  • N,N-Dimethylpyrrolidine-2-carboxamide
  • (S)-N,N-dimethylpyrrolidine-2-carboxamide
  • N,N-dimethylprolinamide(SALTDATA: 0.9HCl)
  • (2S)-N,N-Dimethylpyrrolidine-2-carboxamide
  • L-Proline dimethylamide, N,N-Dimethyl-L-prolinamide
  • H-Pro-NMe
  • (S)-Pyrrolidine-2-carboxylic acid dimethylamide
  • L-Proline dimethylamide98%
  • L-Pro-NMe2
  • (2S)-N,N-DIMETHYL-2-PYRROLIDINECARBOXAMIDE
  • H-PRO-NME2
  • H-PYRD(2)-NME2
  • L-PROLINE-N,N-DIMETHYLAMIDE
  • L-N,N,-DIMETHYL-PROLINAMIDE
  • 2-Pyrrolidinecarboxamide, N,N-dimethyl-, (2S)-
  • H-PRO-NME2 USP/EP/BP
  • (2S)-N,N-Dimethylpyrrolidine-2-carboxamide - [D14239]
  • 29802-22-0
  • Proline [Pro, P]
  • Amino Acids and Derivatives