DM3

Product Name: DM3
CAS No.: 796073-54-6
Chemical Name: DM3
Synonyms: DM3;Maytansinoid DM3;Maytansine, N2'-deacetyl-N2'-(4-mercapto-1-oxopentyl)-
CBNumber: CB93959870
Molecular Formula: C37H52ClN3O10S
Formula Weight: 766.34
MOL File: 796073-54-6.mol

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DM3 Property

Boiling point:: 942.2±65.0 °C(Predicted)
Density: 1.30±0.1 g/cm3(Predicted)
pka: 9.82±0.70(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0104939
Product name: DM3
Packaging: 5mg
Price: $710
Updated: 2021/12/16

ChemScene

Product number: CS-0104939
Product name: DM3
Packaging: 10mg
Price: $1200
Updated: 2021/12/16

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DM3 Chemical Properties,Usage,Production

Uses

DM3 (Maytansinoid DM3), a Maytansine (HY-13674) analog bearing disulfide or thiol groups, and is a tubulin inhibitor. DM3 a cytotoxic moiety of antibody-drug conjugates (ADCs)[1][2].

IC 50

Maytansinoids

References

[1] Chen H, et al. Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy. Molecules. 2017 Aug 1;22(8). DOI:10.3390/molecules22081281
[2] Griffin P, et al. High anti-tumor activity of a novel alpha-fetoprotein-maytansinoid conjugate targeting alpha-fetoprotein receptors in colorectal cancer xenograft model. Cancer Cell Int. 2023 Apr 5;23(1):60. DOI:10.1186/s12935-023-02910-0

DM3 Preparation Products And Raw materials

Raw materials

Preparation Products

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DM3 Suppliers

China 18 United States 4 Global 22

Beijing Jin Ming Biotechnology Co., Ltd.

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796073-54-6, DM3Related Search:

DM3

Maytansinoid DM3

Maytansine, N2'-deacetyl-N2'-(4-mercapto-1-oxopentyl)-

796073-54-6