I-PEG5-OH

Product Name: I-PEG5-OH
CAS No.: 1883516-31-1
Chemical Name: I-PEG5-OH
Synonyms: I-PEG5-OH;I-PEG5-OH MFCD31656975;14-Iodo-3,6,9,12-tetraoxatetradecan-1-ol;3,6,9,12-Tetraoxatetradecan-1-ol, 14-iodo-;I-PEG5-OH/3,6,9,12-Tetraoxatetradecan-1-ol, 14-iodo-
CBNumber: CB93975520
Molecular Formula: C10H21IO5
Formula Weight: 348.18
MOL File: 1883516-31-1.mol

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I-PEG5-OH Property

Boiling point:: 382.0±37.0 °C(Predicted)
Density: 1.479±0.06 g/cm3(Predicted)
pka: 14.36±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS104157
Product name: I-PEG5-OH
Purity: 95+%
Packaging: 250mg
Price: $267
Updated: 2021/12/16

Activate Scientific

Product number: AS104157
Product name: I-PEG5-OH
Purity: 95+%
Packaging: 1g
Price: $530
Updated: 2021/12/16

Activate Scientific

Product number: AS104157
Product name: I-PEG5-OH
Purity: 95+%
Packaging: 5G
Price: $1421
Updated: 2021/12/16

Acrotein

Product number: B-1108
Product name: I-PEG5-OH
Purity: 97%
Packaging: 0.25g
Price: $192.5
Updated: 2021/12/16

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I-PEG5-OH Chemical Properties,Usage,Production

Uses

I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

I-PEG5-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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I-PEG5-OH Suppliers

China 13 Global 13

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Accela ChemBio Co.,Ltd.

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1883516-31-1, I-PEG5-OHRelated Search:

I-PEG5-OH

I-PEG5-OH MFCD31656975

I-PEG5-OH/3,6,9,12-Tetraoxatetradecan-1-ol, 14-iodo-

3,6,9,12-Tetraoxatetradecan-1-ol, 14-iodo-

14-Iodo-3,6,9,12-tetraoxatetradecan-1-ol

1883516-31-1