ChemicalBook > CAS DataBase List > L-R4W2

L-R4W2

Product Name
L-R4W2
CAS No.
206350-79-0
Chemical Name
L-R4W2
Synonyms
L-R4W2;L-Tryptophanamide, L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-tryptophyl- (9CI);(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-Amino-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-car bamimidamido-N-[(1S)-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]pentanamide
CBNumber
CB9402588
Molecular Formula
C46H71N21O6
Formula Weight
1014.19
MOL File
206350-79-0.mol
More
Less

L-R4W2 Property

Density 
1.53±0.1 g/cm3(Predicted)
storage temp. 
Desiccate at -20°C
pka
13.31±0.46(Predicted)
form 
Powder
Water Solubility 
Soluble to 1 mg/ml in water
Sequence
Arg-Arg-Arg-Arg-Trp-Trp-NH2
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Tocris
Product number
1577
Product name
L-R4W2
Packaging
1
Price
$216
Updated
2021/12/16
Usbiological
Product number
255656
Product name
L-R4W2
Packaging
1mg
Price
$516
Updated
2021/12/16
ApexBio Technology
Product number
B5134
Product name
L-R4W2
Packaging
1mg
Price
$377
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0004502
Product name
L-R4W2
Purity
95.00%
Packaging
5MG
Price
$505.29
Updated
2021/12/16
More
Less

L-R4W2 Chemical Properties,Usage,Production

Uses

L-R4W2 is a potent antagonist of vanilloid receptor 1 (VR1, TRPV1), with an IC50 of 0.1 μM. L-R4W2 may act as a potent analgesic[1][2].

IC 50

TRPV1: 0.1 μM (IC50)

References

[1] Planells-Cases R, et, al. Arginine-rich peptides are blockers of VR-1 channels with analgesic activity. FEBS Lett. 2000 Sep 15; 481(2): 131-6. DOI:10.1016/s0014-5793(00)01982-7
[2] Himmel HM, et, al. The arginine-rich hexapeptide R4W2 is a stereoselective antagonist at the vanilloid receptor 1: a Ca2+ imaging study in adult rat dorsal root ganglion neurons. J Pharmacol Exp Ther. 2002 Jun; 301(3): 981-6. DOI:10.1124/jpet.301.3.981

L-R4W2 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

L-R4W2 Suppliers

China 34 Germany 2 United Kingdom 1 United States 6 Global 43
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Creative Peptides
Tel
Email
info@creative-peptides.com
Country
United States
ProdList
6083
Advantage
56
Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4802
Advantage
58
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
7408
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19552
Advantage
58
Hangzhou Go Top Peptide Biotech
Tel
15397062932
Email
sales1@gotopbio.com
Country
China
ProdList
2923
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
Shaoxing Junyu Biotechnology Co., LTD
Tel
0571-0571-88211921 19105816207
Email
sales4@gotopbio.com
Country
China
ProdList
5144
Advantage
58

206350-79-0, L-R4W2Related Search:

H-TRP-TRP-OH L-R4W2

  • L-R4W2
  • L-Tryptophanamide, L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-tryptophyl- (9CI)
  • (2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-Amino-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-5-car bamimidamido-N-[(1S)-1-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]pentanamide
  • 206350-79-0
  • C46H71N21O6
  • Vanilloid/TRPV channel