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Lopinavir EP impurity Q

Product Name
Lopinavir EP impurity Q
CAS No.
667904-94-1
Chemical Name
Lopinavir EP impurity Q
Synonyms
Lopinavir Impurity 17;Lopinavir EP impurity Q;Lopinavir Impurity 17(Lopinavir EP Impurity Q);Acetamide, N,N'-[(1S,2S,4S)-2-hydroxy-1,4-bis(phenylmethyl)-1,4-butanediyl]bis[2-(2,6-dimethylphenoxy)-;N-[(1S,2S,4S)-1-benzyl-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-2-hydroxy-5-phenylpentyl]-2-(2,6-dimethylphenoxy)acetamide,
CBNumber
CB94033593
Molecular Formula
C38H44N2O5
Formula Weight
608.77
MOL File
667904-94-1.mol
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Lopinavir EP impurity Q Property

Boiling point:
864.5±65.0 °C(Predicted)
Density 
1.154±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator (0°C)
solubility 
Chloroform; Dichloromethane; DMSO; Ethyl Acetate; Methanol
pka
13.89±0.46(Predicted)
form 
Solid
color 
White
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Hazard and Precautionary Statements (GHS)

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Lopinavir EP impurity Q Chemical Properties,Usage,Production

Uses

N,N''-2-Hydroxy-1,4-bis(phenylmethyl)-2,6-dimethylphenoxy)acetamide is a by-product from the synthesis of (αS)-3-[2-(2,6-Dimethylphenoxy)acetyl]-N-[(1S,3S,4S)-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide (Lopinavir EP Impurity R) (D476505), an impurity of Lopinavir (L469480), a selective HIV protease inhibitor.

Lopinavir EP impurity Q Preparation Products And Raw materials

Raw materials

Preparation Products

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Lopinavir EP impurity Q Suppliers

Pharmaffiliates Analytics and Synthetics P. Ltd
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