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CARDAMONIN

Product Name
CARDAMONIN
CAS No.
18956-16-6
Chemical Name
CARDAMONIN
Synonyms
Cardamoni;ARDAMONIN;Cardamonin;-3-phenylprop-2-en-1-one;1-(2,4-Dihydroxy-6-methoxyphenyl);(E)-1-(2,4-Dihydroxy-6-methoxy-phenyl)-3-phenyl-;(E)-1-(2,4-DIHYDROXY-6-METHOXY-PHENYL)-3-PHENYL-PROPENONE;1-(2,4-Dihydroxy-6-Methoxyphenyl)-3-phenylprop-2-en-1-one;2-Propen-1-one, 1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenyl-;Natural Alpinia Seed Extract 98% Cardamonin Powder CAS?18956-16-6
CBNumber
CB9411933
Molecular Formula
C16H14O4
Formula Weight
270.28
MOL File
18956-16-6.mol
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CARDAMONIN Property

Melting point:
178 °C
Boiling point:
484.5±45.0 °C(Predicted)
Density 
1.282±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO: 125 mg/mL (462.48 mM)
form 
Solid
pka
7.00±0.40(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D453198
Product name
1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one
Packaging
20mg
Price
$185
Updated
2021/12/16
ChemScene
Product number
CS-0008777
Product name
Cardamonin
Purity
98.54%
Packaging
5mg
Price
$68
Updated
2021/12/16
ChemScene
Product number
CS-0008777
Product name
Cardamonin
Purity
98.54%
Packaging
10mg
Price
$116
Updated
2021/12/16
Oakwood
Product number
032387
Product name
(E)-1-(2,4-Dihydroxy-6-methoxy-phenyl)-3-phenyl-propenone
Packaging
20mg
Price
$130
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000501
Product name
CARDAMONIN
Purity
95.00%
Packaging
5MG
Price
$185.9
Updated
2021/12/16
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CARDAMONIN Chemical Properties,Usage,Production

Uses

1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one is inhibits NO and PGE2 production and inhibits TXB2 production.

Definition

ChEBI: Cardamonin is a member of chalcones.

in vivo

Cardamonin (oral gavage; 20, 40 or 80 mg/kg; once) treatments alleviates doxorubicin-induced cardiotoxicity and inhibits apoptosis in doxorubicin-challenged mice[4].

Animal Model:Male C57BL/6 J mice (8 weeks old, 20-22 g)[4]
Dosage:20, 40 or 80 mg/kg
Administration:Oral gavage; 20, 40 or 80 mg/kg; once
Result:Rescued the reduction of LVEF% and LVFS% by doxorubicin, reduced the increasement of serum LDH, CK-MB and Tn-T levels by doxorubicin in a dose-dependent manner, improved doxorubicin-induced histological changes, and attenuated collagen accumulation in cardiac sections by doxorubicin in a dose-dependent manner.
Animal Model:Male C57BL/6 J mice (8 weeks old, 20-22 g)[4]
Dosage:20, 40 or 80 mg/kg
Administration:Oral gavage; 20, 40 or 80 mg/kg; once
Result:Rescued Bcl-2, and inhibited Bax and Caspase-3 cleavage in heart tissues from doxorubicin-challenged mice.

CARDAMONIN Preparation Products And Raw materials

Raw materials

Preparation Products

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CARDAMONIN Suppliers

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View Lastest Price from CARDAMONIN manufacturers

Shaanxi Xianhe Biotech Co., Ltd
Product
Cardamomin 18956-16-6
Price
US $0.00/KG
Min. Order
1KG
Purity
0.99
Supply Ability
1000KG
Release date
2025-05-06
Hebei Chuanghai Biotechnology Co., Ltd
Product
CARDAMONIN 18956-16-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-25
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
CARDAMONIN 18956-16-6
Price
US $35.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/Week
Release date
2024-05-07

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