1,8-NAPHTHOSULTAM
- Product Name
- 1,8-NAPHTHOSULTAM
- CAS No.
- 603-72-5
- Chemical Name
- 1,8-NAPHTHOSULTAM
- Synonyms
- 1,8-NAPHTHOSULTAM;1,8-Naphthasultam;1,8-Naphthosultam,98%;1,8-NAPHTHALENESULTAM;2H-naphth[1,8-cd]isothiazole 1,1-dioxide;2H-naphtho[1,8-cd]isothiazole 1,1-dioxide;8-Aminonaphthalene-1-sulfonic acid sultam;1,2-Napthaquinone-4-SulphonicacidSodiumSalt
- CBNumber
- CB9417243
- Molecular Formula
- C10H7NO2S
- Formula Weight
- 205.23
- MOL File
- 603-72-5.mol
1,8-NAPHTHOSULTAM Property
- Melting point:
- 173-175 °C(lit.)
- Boiling point:
- 442.2±28.0 °C(Predicted)
- Density
- 1.3178 (rough estimate)
- refractive index
- 1.5250 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 4122CA
- Product name
- 2H-Naphth(1,8-cd)isothiazole1,1-dioxide
- Packaging
- 250mg
- Price
- $132
- Updated
- 2021/12/16
- Product number
- 4122CA
- Product name
- 2H-Naphth(1,8-cd)isothiazole1,1-dioxide
- Packaging
- 2.5g
- Price
- $174
- Updated
- 2021/12/16
- Product number
- CHM0017457
- Product name
- 1,8-NAPHTHALENESULTAM
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $831.95
- Updated
- 2021/12/16
- Product number
- CD11096112
- Product name
- 2H-Naphtho[1,8-cd]isothiazole1,1-dioxide
- Purity
- 95+%
- Packaging
- 5g
- Price
- $127
- Updated
- 2021/12/16
- Product number
- MT-19281
- Product name
- 1,8-Naphthalenesultam
- Purity
- 97%
- Packaging
- 250g
- Price
- $330
- Updated
- 2021/12/16
1,8-NAPHTHOSULTAM Chemical Properties,Usage,Production
Chemical Properties
grey-green to brown-grey or grey powder
Synthesis
16619-06-0
603-72-5
General procedure for the synthesis of 1,8-naphthalenesulfonolactam from 1,8-naphthalenesulfonic acid potassium salt (CAS: 16619-06-0): 5 g of 1,8-naphthalenesulfonic acid potassium salt was pulverized and placed in a flask containing 15 g of POCl3. After installation of a reflux condenser, the reaction system is heated in an oil bath to 130°C. When the temperature reaches 100°C, HCl gas starts to be released, which has to be discharged through the flue. To facilitate the reaction, the flask was shaken periodically. After the release of irritating gases stops, the heating is continued until the reaction mixture no longer produces dye in the diazotization and color development test, usually for a reaction time of 3 hours. Due to the slurry-like consistency of the reaction mixture, caution is required to remove excess POCl3. Subsequently, the reaction mixture is quenched by slowly pouring it into an ice bath. The gray solid product was collected by diafiltration and washed repeatedly with water to remove most of the phosphoric acid. The crude product was dried and purified by recrystallization with benzene. Product melting point: 175-180°C; 1H NMR (DMSO-d6, 300 MHz) δ: 8.62 (d, 1H, J = 8.0 Hz), 8.12 (d, 1H, J = 8.0 Hz), 7.75-7.74 (m, 1H), 7.61 (d, 1H, J = 8.0 Hz), 7.32 (dd, 1H, J = 7.5, 6.7 Hz), 6.7 Hz), 6.7 Hz). 6.7 Hz), 6.90 (d, 1H, J = 6.8 Hz), 5.36 (s, 1H); MS (EI): m/z 206 (M++H).
References
[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 2, p. 789 - 800
[2] Tetrahedron, 2014, vol. 70, # 8, p. 1659 - 1690
1,8-NAPHTHOSULTAM Preparation Products And Raw materials
Raw materials
Preparation Products
1,8-NAPHTHOSULTAM Suppliers
- Tel
- --
- Fax
- --
- sales21@chemicalland21.com
- Country
- South Korea
- ProdList
- 6303
- Advantage
- 74
View Lastest Price from 1,8-NAPHTHOSULTAM manufacturers
- Product
- 1,8-Naphthosultam 603-72-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 2000tons
- Release date
- 2025-08-15