3-CHLORO-5-HYDROXYBENZALDEHYDE
- Product Name
- 3-CHLORO-5-HYDROXYBENZALDEHYDE
- CAS No.
- 1829-33-0
- Chemical Name
- 3-CHLORO-5-HYDROXYBENZALDEHYDE
- Synonyms
- 3-CHLORO-5-HYDROXYBENZALDEHYDE;Benzaldehyde, 3-chloro-5-hydroxy-
- CBNumber
- CB9419267
- Molecular Formula
- C7H5ClO2
- Formula Weight
- 156.57
- MOL File
- 1829-33-0.mol
3-CHLORO-5-HYDROXYBENZALDEHYDE Property
- Melting point:
- 104 °C
- Boiling point:
- 268.3±20.0 °C(Predicted)
- Density
- 1.404±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 8.28±0.10(Predicted)
- Appearance
- Light brown to brown Solid
Safety
- HS Code
- 2912490090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- C360330
- Product name
- 3-Chloro-5-hydroxybenzaldehyde
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 079714
- Product name
- 3-Chloro-5-hydroxybenzaldehyde
- Purity
- 97%
- Packaging
- 5g
- Price
- $192
- Updated
- 2021/12/16
- Product number
- FC142342
- Product name
- 3-Chloro-5-hydroxybenzaldehyde
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 076415
- Product name
- 3-Chloro-5-hydroxybenzaldehyde
- Purity
- 95+%
- Packaging
- 1g
- Price
- $89
- Updated
- 2021/12/16
- Product number
- 2615-5-31
- Product name
- 3-Chloro-5-hydroxybenzaldehyde
- Purity
- 98%
- Packaging
- 1g
- Price
- $116
- Updated
- 2021/12/16
3-CHLORO-5-HYDROXYBENZALDEHYDE Chemical Properties,Usage,Production
Synthesis
164650-68-4
1829-33-0
Using 3-chloro-5-methoxybenzaldehyde (22.8 g, 134 mmol) as starting material, it was dissolved in dichloromethane (250 mL) and the solution was cooled to 0°C. Boron tribromide (15.8 mL, 167 mmol) was slowly added dropwise over a period of 15 min. After the dropwise addition was completed, the reaction mixture continued to be stirred at 0°C for 2 hr. Subsequently, water (50 mL) was added slowly to quench the reaction. The reaction mixture was extracted with ether (2 x 100 mL), the organic layers were combined, dried over anhydrous sodium sulfate, filtered and concentrated in vacuum. Purification by silica gel column chromatography using hexane: ethyl acetate (4:1) as eluent gave the target product 3-chloro-5-hydroxybenzaldehyde (5.2 g, 25% yield). The product was confirmed by 1H NMR (300 MHz, CDCl3): δ 9.85 (s, 1H), 7.35 (s, 1H), 7.20 (s, 1H), 7.10 (s, 1H), 3.68 (s, 1H).
References
[1] Patent: WO2003/101957, 2003, A1. Location in patent: Page 29-30
[2] Patent: US2004/19033, 2004, A1. Location in patent: Page/Page column 16
[3] Patent: WO2003/101423, 2003, A1. Location in patent: Page 19-20
[4] Patent: WO2003/101424, 2003, A1. Location in patent: Page 21-22
[5] Patent: WO2003/101956, 2003, A1. Location in patent: Page 40
3-CHLORO-5-HYDROXYBENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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