(+/-)-MUSCARINE CHLORIDE

Product Name: (+/-)-MUSCARINE CHLORIDE
CAS No.: 2936-25-6
Chemical Name: (+/-)-MUSCARINE CHLORIDE
Synonyms: (+)-MUSCARINE;Muscarinic chloride;DL-MUSCARINCHLORIDE);DL-MUSCARINECHLORIDE;(+/-)-MUSCARINE CHLORIDE;(±)-Muscarine chloride hydrate;(+/-)-muscarine chloride approx. 95%;(+/-)-MUSCARINE CHLORIDE SYNTHETIC >99%;(±)-Muscarine chloride hydrate in methanol;Tetrahydro-4α-hydroxy-N,N,N,5β-tetramethyl-2β-furanmethanaminium
CBNumber: CB9427721
Molecular Formula: C9H20ClNO2
Formula Weight: 209.71
MOL File: 2936-25-6.mol

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(+/-)-MUSCARINE CHLORIDE Property

storage temp.: room temp
solubility: deionized water: ≥20mg/mL
form: powder
color: white

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Safety

Hazard Codes: Xn
Risk Statements: 22-36
Safety Statements: 26-36
RIDADR: 1544
WGK Germany: 3
HazardClass: 6.1(a)
PackingGroup: II

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M104
Product name: (±)-Muscarine chloride hydrate
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $167
Updated: 2024/03/01

Sigma-Aldrich

Product number: M104
Product name: (±)-Muscarine chloride hydrate
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $537
Updated: 2024/03/01

TRC

Product number: M814005
Product name: (+/-)-MuscarineChloride
Packaging: 25mg
Price: $1175
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HBL0000023
Product name: (+/-)-MUSCARINE CHLORIDE
Purity: 95.00%
Packaging: 5MG
Price: $578
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HBL0000023
Product name: (+/-)-MUSCARINE CHLORIDE
Purity: 95.00%
Packaging: 10MG
Price: $883.49
Updated: 2021/12/16

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(+/-)-MUSCARINE CHLORIDE Chemical Properties,Usage,Production

Description

Muscarine is a natural alkaloid that is found in a number of wild mushrooms. Despite the fact that muscarine does not have any therapeutic value, it is of interest because of its expressed toxic properties, which made it one of the first systematically studied cholinomimetic substances. This compound was an underlying classification of cholinergic muscarinic receptors. The action of muscarine is similar to that of acetylcholine on peripheral autonomic effector organs, and atropine is an antagonist to it. Unlike acetylcholine, muscarine does not act on nicotinic receptors.

Uses

(+/-)-Muscarine Chloride is a muscarinic acteylcholine receptor agonist.

Biochem/physiol Actions

Muscarine is a potent agonist than acetylcholine and is not susceptible to degradation by cholinesterases. Muscarine administration results in muscle spasm especially in gut, bronchus and uterus.

Synthesis

Muscarine, 2-methyl-3-hydroxy-5-(N,N,N-trimethylammonium) methylentetrahydrofuran chloride (13.1.14), was first isolated from the poisonous mushrooms Amanita muscaria. It can be synthesized in various ways from completely different substances [16¨C24], particularly from 2,5-dimethyl-3-carboxymethylflurane, which undergoes a Curtius reaction, i.e. successive reactions with hydrazine and further with nitrous acid in isopropyl alcohol, which forms the urethane (13.1.9), the acidic hydrolysis of which gives 2,5-dimethyl-2H-furane-3 (13.1.10). Allylic bromination of this gives 2- methyl-5-bromomethyl-2H-furanone-3 (13.1.11), which is reacted with dimethylamine, forming 2-methyl-5-dimethylaminomethyl-2H-fluranone-3 (13.1.12). Reducing this compound leads to formation of 2-methyl-3-hydroxy-5-dimethylaminomethyltetrahydroflurane (13.1.13), the reaction of which with methyl chloride gives muscarine (13.1.14) as a mixture of stereoisomers.

(+/-)-MUSCARINE CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-MUSCARINE CHLORIDE Suppliers

China 13 Germany 1 South Korea 1 Sweden 1 Switzerland 1 United States 5 Global 22

3B Pharmachem (Wuhan) International Co.,Ltd.

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Sigma-Aldrich

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Country: China
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Shanghai Moqi Biological Technology Co., LTD

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Country: China
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TargetMol Chemicals Inc.

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Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
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Shandong Mopai Biotechnology Co., Ltd

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TargetMol Chemicals Inc.

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Country: United States
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Zibo Hangyu Biotechnology Development Co., Ltd

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Email: Mandy@hangyubiotech.com
Country: China
ProdList: 10986
Advantage: 58

United States Biological

Tel: --
Fax: --
Email: sales@advtechind.com
Country: United States
ProdList: 6075
Advantage: 58

2936-25-6, (+/-)-MUSCARINE CHLORIDERelated Search:

(+)-MUSCARINE CHLORIDE N-METHYLTETRAHYDROFURFURYLAMINE β-Methylcholine Chloride (+/-)-MUSCARINE CHLORIDE (+/-)-MUSCARINE CHLORIDE 2-Tetrahydrofurfurylamine

(+)-MUSCARINE

(+/-)-MUSCARINE CHLORIDE

TETRAHYDRO-4-HYDROXY-N,N,N,5-TETRAMETHYL-2-FURANMETHANAMMONIUM CHLORIDE

(+/-)-muscarine chloride approx. 95%

(+/-)-MUSCARINE CHLORIDE SYNTHETIC >99%

DL-MUSCARINECHLORIDE

DL-MUSCARINCHLORIDE)

(-)-α-[[(2R)-Tetrahydro-4α-hydroxy-5β-methylfuran]-2β-yl]-N,N,N-trimethylmethanaminium

(2R)-Tetrahydro-4α-hydroxy-N,N,N,5β-tetramethyl-2β-furanmethanaminium

(2R,4S,5R)-Tetrahydro-4-hydroxy-5,N,N,N-tetramethyl-2-furanmethanaminium

[(4α-Hydroxy-5β-methyltetrahydrofuran-2β-yl)methyl]trimethylaminium

Tetrahydro-4α-hydroxy-N,N,N,5β-tetramethyl-2β-furanmethanaminium

rac-(2S*)-Tetrahydro-4β*-hydroxy-N,N,N,5α*-tetramethyl-2α*-furanmethanaminium

2-Furanmethanaminium, tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-, chloride, (2alpha,4beta,5alpha)-(+-)-

(±)-Muscarine chloride hydrate

Tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-2-furanmethanammonium chloride hydrate

Muscarinic chloride

(±)-Muscarine chloride hydrate in methanol

2936-25-6

C9H20NO2