7-DIETHYLAMINO-4-(TRIFLUOROMETHYL)COUMARIN

7-DIETHYLAMINO-4-(TRIFLUOROMETHYL)COUMARIN Property

Melting point:

80-81 °C

Boiling point:

352.7±42.0 °C(Predicted)

Density 

1.405 g/cm3

storage temp. 

2-8°C, protect from light

pka

2.74±0.20(Predicted)

form 

powder to crystal

color 

Yellow to Brown to Dark green

Appearance

Yellow to Brown to Dark green powder to crystal

λmax

411nm(H2O)(lit.)

InChI

InChI=1S/C14H14F3NO2/c1-3-18(4-2)9-5-6-10-11(14(15,16)17)8-13(19)20-12(10)7-9/h5-8H,3-4H2,1-2H3

InChIKey

UIMOXRDVWDLOHW-UHFFFAOYSA-N

SMILES

C1(=O)OC2=CC(N(CC)CC)=CC=C2C(C(F)(F)F)=C1

EPA Substance Registry System

2H-1-Benzopyran-2-one, 7-(diethylamino)-4-(trifluoromethyl)- (41934-47-8)

Safety

WGK Germany 

3

HS Code 

2916399090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

7-DIETHYLAMINO-4-(TRIFLUOROMETHYL)COUMARIN Chemical Properties,Usage,Production

Uses

7-DIETHYLAMINO-4-(TRIFLUOROMETHYL)COUMARIN is a laser dye with high laser conversion efficiency and relatively stable performance, belonging to the blue-green light band. It is used in tunable dye lasers pumped by flash lamps, argon ions, krypton ions, etc.

Description

Coumarin 481 is a multifaceted biomedical compound that can be used in pharmaceutical research for a variety of diseases. Noteworthy for its potent anticoagulant effects, as well as its impressive anti-inflammatory and anti-cancer attributes, Coumarin 481 has garnered considerable attention. Extensive examination has underscored its remarkable capacity to impede neoplastic expansion, avert thrombus genesis, and assuage chronically persistent inflammatory states.

Chemical Properties

Coumarin-35 scientific name is 7-diethylamino-4-trifluoromethylcoumarin, which is yellow-green feathery crystalline. Melting point 78~81℃. Soluble in methanol, ethanol, dioxane, its solution shows green fluorescence.

Definition

ChEBI: Coumarin 481 is a member of 7-aminocoumarins. It has a role as a fluorochrome.