3-Methoxybenzamide
- Product Name
- 3-Methoxybenzamide
- CAS No.
- 5813-86-5
- Chemical Name
- 3-Methoxybenzamide
- Synonyms
- 3-MBA;3-ANISAMIDE;M-ANISAMIDE;3-methoxy-benzamid;M-METHOXYBENZAMIDE;3-METHOXYBENZAMIDE;Benzamide, 3-methoxy-;FtsZ,ADPRT,PARP,3 Methoxybenzamide,microtuber,Bacterial,3-Methoxybenzamide,inhibit,poly ADP ribose polymerase,Inhibitor,3Methoxybenzamide
- CBNumber
- CB9446689
- Molecular Formula
- C8H9NO2
- Formula Weight
- 151.16
- MOL File
- 5813-86-5.mol
3-Methoxybenzamide Property
- Melting point:
- 132.5-135.5 °C (lit.)
- Boiling point:
- 280.0±23.0 °C(Predicted)
- Density
- 1.143±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml,Ethanol: 1 mg/ml
- form
- A crystalline solid
- pka
- 15.81±0.50(Predicted)
- Water Solubility
- Soluble in water.
- BRN
- 2206857
- InChI
- InChI=1S/C8H9NO2/c1-11-7-4-2-3-6(5-7)8(9)10/h2-5H,1H3,(H2,9,10)
- InChIKey
- VKPLPDIMEREJJF-UHFFFAOYSA-N
- SMILES
- C(N)(=O)C1=CC=CC(OC)=C1
- CAS DataBase Reference
- 5813-86-5(CAS DataBase Reference)
Safety
- WGK Germany
- 3
- RTECS
- CV5463333
- HS Code
- 2924297099
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M10050
- Product name
- 3-Methoxybenzamide
- Purity
- 97%
- Packaging
- 5g
- Price
- $111
- Updated
- 2024/03/01
- Product number
- B23204
- Product name
- 3-Methoxybenzamide
- Purity
- 97%
- Packaging
- 5g
- Price
- $34.1
- Updated
- 2021/12/16
- Product number
- 30451
- Product name
- m-Methoxybenzamide
- Packaging
- 5g
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 30451
- Product name
- m-Methoxybenzamide
- Packaging
- 10g
- Price
- $115
- Updated
- 2024/03/01
- Product number
- 30451
- Product name
- m-Methoxybenzamide
- Packaging
- 25g
- Price
- $270
- Updated
- 2024/03/01
3-Methoxybenzamide Chemical Properties,Usage,Production
Uses
3-Methoxybenzamide is act as an inhibitor of ADP-ribosyltransferase. It is also a weak inhibitor of the essential bacterial cell division protein FtsZ. Alkyl derivatives of 3-Methoxybenzamide are potent antistaphylococcal compounds with suboptimal drug-like properties.
Biological Activity
3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum).
in vitro
3-Methoxybenzamide (0-30 mM) affects septation via the FtsZ system during both vegetative growth and sporulation. 3-Methoxybenzamide (3 MB; 0.2 to 0.6 mM) significantly increaseS the growth and microtuber formation of in vitro propagated plants.