ChemicalBook > CAS DataBase List > methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
- Product Name
- methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
- CAS No.
- 1902955-29-6
- Chemical Name
- methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
- Synonyms
- Fexuprazan P-4;Fexuprazan Impurity3;Abeprazan Impurity 1;Fexuprazan intermediate;Methyl 5-(2,4-Difluorophenyl)-4-methoxypyrrole-3-carboxylate;methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate;1H-Pyrrole-3-carboxylic acid, 5-(2,4-difluorophenyl)-4-methoxy-, methyl ester;5-?(2,?4-?difluorophenyl)?-?4-?methoxy-?1H-?Pyrrole-?3-?carboxylic acid methyl ester;2-Butenoicacid,2-hydroxy-4-[3-methyl-4-(phenylmethoxy)phenyl]-4-oxo-,methylester,(5Z)-
- CBNumber
- CB94663743
- Molecular Formula
- C13H11F2NO3
- Formula Weight
- 267.23
- MOL File
- 1902955-29-6.mol
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methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate Property
- Boiling point:
- 409.4±45.0 °C(Predicted)
- Density
- 1.314±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- pka
- 13.95±0.50(Predicted)
- Appearance
- White to yellow Solid
- InChI
- InChI=1S/C13H11F2NO3/c1-18-12-9(13(17)19-2)6-16-11(12)8-4-3-7(14)5-10(8)15/h3-6,16H,1-2H3
- InChIKey
- DMNUDNHYRCDZDC-UHFFFAOYSA-N
- SMILES
- N1C(C2=CC=C(F)C=C2F)=C(OC)C(C(OC)=O)=C1
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N-Bromosuccinimide Price
Ambeed
- Product number
- A941869
- Product name
- Methyl5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
- Purity
- 98%
- Packaging
- 100mg
- Price
- $33
- Updated
- 2021/12/16
Ambeed
- Product number
- A941869
- Product name
- Methyl5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
- Purity
- 98%
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
Ambeed
- Product number
- A941869
- Product name
- Methyl5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
- Purity
- 98%
- Packaging
- 1g
- Price
- $155
- Updated
- 2021/12/16
Chemenu
- Product number
- CM333146
- Product name
- Methyl5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
- Purity
- 95%+
- Packaging
- 1g
- Price
- $216
- Updated
- 2021/12/16
Ambeed
- Product number
- A941869
- Product name
- Methyl5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate
- Purity
- 98%
- Packaging
- 5g
- Price
- $557
- Updated
- 2021/12/16
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methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate Chemical Properties,Usage,Production
Uses
Methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate is used as an intermediate for fexuprazan, a novel potassium-competitive acid blocker for the treatment of gastroesophageal reflux disease (GERD).
Synthesis
Methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate can be prepared by the following routes[1]:
References
[1] TING WANG. Scalable Synthesis of the Key Fexuprazan Intermediate and Investigation of a Reaction Mechanism.[J]. ACS Omega, 2024, 9 36: 37942-37952. DOI:10.1021/acsomega.4c04507.
methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate Preparation Products And Raw materials
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View Lastest Price from methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate manufacturers
Shanghai Joiny Pharmaceutical Co.,LTD
- Product
- 5-(2,4-difluorophenyl)-4-methoxy-1H-Pyrrole-3-carboxylic acid methyl ester 1902955-29-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2025-09-22
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate 1902955-29-6
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-19
Beijing Toachem Chemical Co.,Ltd
- Product
- methyl 5-(2,4-difluorophenyl)-4-methoxy-1H-pyrrole-3-carboxylate 1902955-29-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 30t
- Release date
- 2025-01-06