ChemicalBook > CAS DataBase List > 4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine

4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine

Product Name
4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine
CAS No.
108237-91-8
Chemical Name
4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine
Synonyms
RC D423;RCGD423;RCGD 432;N-(4-Bromophenyl)-4-phenylthiazol-2-amine;2-Thiazolamine, N-(4-bromophenyl)-4-phenyl-;4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine;Regulator of cartilage growth and differentiation (RCGD) 423;RCGD423,inhibit,RCGD 423,Inhibitor,Interleukin Related,RCGD-423
CBNumber
CB94664083
Molecular Formula
C15H11BrN2S
Formula Weight
331.23
MOL File
108237-91-8.mol
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4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine Property

storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMSO:34.0(Max Conc. mg/mL);102.6(Max Conc. mM)
Ethanol:34.0(Max Conc. mg/mL);102.6(Max Conc. mM)
form 
A solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris
Product number
7066
Product name
RCGD423
Purity
≥98%(HPLC)
Packaging
50
Price
$125
Updated
2021/12/16
ChemScene
Product number
CS-0064289
Product name
RCGD423
Purity
99.78%
Packaging
10mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-0064289
Product name
RCGD423
Purity
99.78%
Packaging
5mg
Price
$90
Updated
2021/12/16
ChemScene
Product number
CS-0064289
Product name
RCGD423
Purity
99.78%
Packaging
25mg
Price
$200
Updated
2021/12/16
ChemScene
Product number
CS-0064289
Product name
RCGD423
Purity
99.78%
Packaging
50mg
Price
$290
Updated
2021/12/16
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4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine Chemical Properties,Usage,Production

Biological Activity

RCGD-423 is a Glycoprotein 130 (gp130, IL6ST, IL6-beta, CD130) signaling regulator that regulates cartilage growth and differentiation.

in vitro

RCGD423 is a gp130 modulator, which prevents articular cartilage degeneration and promotes repair.

in vivo

RCGD423 greatly reduces chondrocyte hypertrophy, loss and degeneration while increasing chondrocyte proliferation beyond that observed in response to injury in a rat partial meniscectomy model. Moreover, RCGD 423 improves cartilage healing in a rat full-thickness osteochondral defect model,

target

IL6-beta

< span>

storage

Store at -20°C

4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine Suppliers

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108237-91-8, 4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amineRelated Search:


  • 4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine
  • RCGD423
  • 2-Thiazolamine, N-(4-bromophenyl)-4-phenyl-
  • RCGD 432
  • N-(4-Bromophenyl)-4-phenylthiazol-2-amine
  • RCGD423,inhibit,RCGD 423,Inhibitor,Interleukin Related,RCGD-423
  • Regulator of cartilage growth and differentiation (RCGD) 423
  • RC D423
  • 108237-91-8