N6-(4-Trifluoromethylbenzyl)adenosine

Product Name: N6-(4-Trifluoromethylbenzyl)adenosine
CAS No.: 722505-71-7
Chemical Name: N6-(4-Trifluoromethylbenzyl)adenosine
Synonyms: N6-(4-Trifluoromethylbenzyl)adenosine;Adenosine, N-?[[4-?(trifluoromethyl)?phenyl]?methyl]?-;(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((4-(trifluoromethyl)benzyl)amino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
CBNumber: CB94672527
Molecular Formula: C18H18F3N5O4
Formula Weight: 425.36
MOL File: 722505-71-7.mol

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N6-(4-Trifluoromethylbenzyl)adenosine Property

Melting point:: 151-153 °C
Boiling point:: 675.9±65.0 °C(Predicted)
Density: 1.70±0.1 g/cm3(Predicted)
pka: 13.11±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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N6-(4-Trifluoromethylbenzyl)adenosine Chemical Properties,Usage,Production

Uses

N-[[4-(Trifluoromethyl)phenyl]methyl]adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020

N6-(4-Trifluoromethylbenzyl)adenosine Preparation Products And Raw materials

Raw materials

Preparation Products

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N6-(4-Trifluoromethylbenzyl)adenosine Suppliers

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722505-71-7, N6-(4-Trifluoromethylbenzyl)adenosineRelated Search:

para-TOPOLIN RIBOSIDE(pTR) N6-(3-Trifluoromethylbenzyl)-2'-C-methyl adenosine N6-(4-Methoxybenzyl)-2'-C-methyl adenosine N6-(3-Methoxybenzyl)-2'-C-methyl adenosine N6-(3-Trifluoromethylbenzyl)adenosine N6-(3-Trifluoromethylbenzyl)-3'-deoxyadenosine

N6-(4-Trifluoromethylbenzyl)adenosine

Adenosine, N-?[[4-?(trifluoromethyl)?phenyl]?methyl]?-

(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((4-(trifluoromethyl)benzyl)amino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol

722505-71-7