ChemicalBook > CAS DataBase List > ZLD-1039
ZLD-1039
- Product Name
- ZLD-1039
- CAS No.
- 1826865-46-6
- Chemical Name
- ZLD-1039
- Synonyms
- ZLD-1039;3-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-N-[(2;8-hexahydro-1-methyl-3-oxo-4-isoquinolinyl)methyl]-2-methyl-5-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-benzamide;3-[ethyl(oxan-4-yl)amino]-2-methyl-N-[(1-methyl-3-oxo-2,3,5,6,7,8-hexahydroisoquinolin-4-yl)methyl]-5-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]benzamide;3-(Ethyl(tetrahydro-2H-pyran-4-yl)amino)-2-methyl-N-((1-methyl-3-oxo-2,3,5,6,7,8-hexahydroisoquinolin-4-yl)methyl)-5-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)benzamide;3-[ETHYL(TETRAHYDRO-2H-PYRAN-4-YL)AMINO]-N-[(2;3;5;6;7;8-HEXAHYDRO-1-METHYL-3-OXO-4-ISOQUINOLINYL)METHYL]-2-METHYL-5-[6-(4-METHYL-1-PIPERAZINYL)-3-PYRIDINYL]-BENZAMIDE;Benzamide, 3-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-N-[(2,3,5,6,7,8-hexahydro-1-methyl-3-oxo-4-isoquinolinyl)methyl]-2-methyl-5-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-
- CBNumber
- CB94674172
- Molecular Formula
- C36H48N6O3
- Formula Weight
- 612.8
- MOL File
- 1826865-46-6.mol
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ZLD-1039 Property
- Boiling point:
- 826.8±65.0 °C(Predicted)
- Density
- 1.24±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: soluble
- form
- A crystalline solid
- pka
- 12.15±0.60(Predicted)
- color
- Off-white to gray
- InChIKey
- SZAYCVHJDOWSNY-UHFFFAOYSA-N
- SMILES
- C(NCC1=C2C(=C(C)NC1=O)CCCC2)(=O)C1=CC(C2=CC=C(N3CCN(C)CC3)N=C2)=CC(N(CC)C2CCOCC2)=C1C
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 19218
- Product name
- ZLD1039
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $90
- Updated
- 2026/04/30
Cayman Chemical
- Product number
- 19218
- Product name
- ZLD1039
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $392
- Updated
- 2026/04/30
Cayman Chemical
- Product number
- 19218
- Product name
- ZLD1039
- Packaging
- 1mg
- Price
- $81
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 19218
- Product name
- ZLD1039
- Packaging
- 5mg
- Price
- $356
- Updated
- 2024/03/01
Tocris
- Product number
- 5847
- Product name
- ZLD1039
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $195
- Updated
- 2021/12/16
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ZLD-1039 Chemical Properties,Usage,Production
Uses
ZLD1039 is a potent, highly selective, and orally bioavailable EZH2 inhibitor. ZLD1039 shows potent and concentration-dependent inhibition of PRC2 enzymatic activity against EZH2 wild-type as well as Y641F, and A677G mutant enzymes with IC50 values of 5.6, 15, and 4.0nM, respectively. ZLD1039 inhibits breast tumor growth and metastasis[1].
storage
Store at -20°C
References
[1] Xuejiao Song, et al. Selective inhibition of EZH2 by ZLD1039 blocks H3K27methylation and leads to potent anti-tumor activity in breast cancer. Sci Rep. 2016; 6: 20864.
ZLD-1039 Preparation Products And Raw materials
Raw materials
Preparation Products
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ZLD-1039 Suppliers
- Tel
- 021-52996696,15000506266 15000506266
- Fax
- +86-21-52996696
- Country
- China
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- United States
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- China
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- China
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