ChemicalBook > CAS DataBase List > Mitochonic acid 5

Mitochonic acid 5

Product Name: Mitochonic acid 5
CAS No.: 1354707-41-7
Chemical Name: Mitochonic acid 5
Synonyms: Mitochonic acid;Mitochonic acid 5;Mitochonic acid 5(MA-5);Mitochonic acid 5, 10 mM in DMSO;α-[2-(2,4-Difluorophenyl)-2-oxoethyl]-1H-indole-3-acetic Acid;1H-Indole-3-acetic acid, α-[2-(2,4-difluorophenyl)-2-oxoethyl]-;MA5,Inhibitor,Mitochonic acid5,Mitochonic acid-5,Mitochondrial Metabolism,Mitochonic acid 5,inhibit,MA 5
CBNumber: CB94718636
Molecular Formula: C18H13F2NO3
Formula Weight: 329.3
MOL File: 1354707-41-7.mol

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Mitochonic acid 5 Property

Boiling point:: 573.3±50.0 °C(Predicted)
Density: 1.426±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:106.66(Max Conc. mg/mL);323.9(Max Conc. mM)
form: A solid
pka: 4.52±0.37(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D447895
Product name: α-[2-(2,4-Difluorophenyl)-2-oxoethyl]-1H-indole-3-aceticAcid
Packaging: 2.5mg
Price: $220
Updated: 2021/12/16

Axon Medchem

Product number: Axon3197
Product name: Mitochonicacid5-MA-5
Purity: 98%
Packaging: 2x5mg
Price: $154
Updated: 2021/12/16

ChemScene

Product number: CS-0043233
Product name: Mitochonicacid5
Purity: 99.37%
Packaging: 5mg
Price: $130
Updated: 2021/12/16

ChemScene

Product number: CS-0043233
Product name: Mitochonicacid5
Purity: 99.37%
Packaging: 10mg
Price: $230
Updated: 2021/12/16

ChemScene

Product number: CS-0043233
Product name: Mitochonicacid5
Purity: 99.37%
Packaging: 25mg
Price: $460
Updated: 2021/12/16

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Mitochonic acid 5 Chemical Properties,Usage,Production

Uses

α-[2-(2,4-Difluorophenyl)-2-oxoethyl]-1H-indole-3-acetic Acid, is a derivative of the plant hormone indole-3-acetic acid, improves survival of fibroblasts from patients with mitochondrial diseases.

Biological Activity

Mitochonic Acid 5 is a potent enhancer of mitochondrial ATP production th at significantly increased the cellular ATP level in Hep3B human hepatocellular carcinoma cells. Mitochonic Acid 5 improves the survival of fibroblasts from patients with mitochondrial diseases. It appears th at mitochonic Acid 5 facilitates ATP synthase oligomerization and supercomplex formation with mitofilin/Mic60.

in vivo

Administration of Mitochonic acid 5 (MA-5) to an ischemia-reperfusion injury model and a cisplatin-induced nephropathy model improved renal function. To examine the tissue-protective effect of Mitochonic acid 5, the oral bioavailability is examined. Oral administration of Mitochonic acid 5 increases the plasma concentration in a dose-response manner at the peak time of 1 hour^[1].

Mitochonic acid 5 Preparation Products And Raw materials

Raw materials

Preparation Products

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1354707-41-7, Mitochonic acid 5Related Search:

Mitochonic acid 5

Mitochonic acid

1H-Indole-3-acetic acid, α-[2-(2,4-difluorophenyl)-2-oxoethyl]-

Mitochonic acid 5(MA-5)

α-[2-(2,4-Difluorophenyl)-2-oxoethyl]-1H-indole-3-acetic Acid

MA5,Inhibitor,Mitochonic acid5,Mitochonic acid-5,Mitochondrial Metabolism,Mitochonic acid 5,inhibit,MA 5

Mitochonic acid 5, 10 mM in DMSO

1354707-41-7

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