LUCIDIN

ChemicalBook > CAS DataBase List > LUCIDIN

Product Name: LUCIDIN
CAS No.: 478-08-0
Chemical Name: LUCIDIN
Synonyms: henine;LUCIDIN;CS-1096;NSC 30546;Lucidin-RM;Lucidin, BR;Lucidin【quinone】;HENINE; NSC 30546;NSC 30546|||Henine;Lucidin (NSC 30546)
CBNumber: CB9475944
Molecular Formula: C15H10O5
Formula Weight: 270.24
MOL File: 478-08-0.mol

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LUCIDIN Property

Melting point:: >330℃
Boiling point:: 333.35°C (rough estimate)
Density: 1.592±0.06 g/cm3 (20 ºC 760 Torr)
refractive index: 1.6000 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: Soluble in DMSO
form: Solid
pka: 6.83±0.20(Predicted)
color: Light yellow to yellow

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Safety

Hazardous Substances Data: 478-08-0(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H350May cause cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Usbiological

Product number: 361821
Product name: Lucidin
Packaging: 10mg
Price: $632
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PXT0001996
Product name: LUCIDIN
Purity: 95.00%
Packaging: 5MG
Price: $499.62
Updated: 2021/12/16

ApexBio Technology

Product number: A3562
Product name: Lucidin
Packaging: 10mg
Price: $541
Updated: 2021/12/16

AK Scientific

Product number: 3789AH
Product name: Lucidin
Packaging: 50mg
Price: $1207
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb181034
Product name: Lucidin (NSC 30546)
Purity: >98%
Packaging: 250mg
Price: $1356.6
Updated: 2021/12/16

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LUCIDIN Chemical Properties,Usage,Production

Definition

ChEBI: Lucidin is a dihydroxyanthraquinone.

Biological Activity

lucidin (nsc 30546) is a natural component of rubia tinctorum l., which is mutagenic in bacteria and mammalian cells [1].hydroxyanthraquinones (has) are special organic compounds widely distributed in the plant kingdom. the ha plants have been used as laxatives and colorant for thousands of years. in the last century, has were also employed as medicine for the treatment of kidney stone. lucidin is a ha extracted from the root of rubia tinctorum l. that also known as madder. it was thought to be genotoxic in bacteria and mammalian cells [1].lucidin was found to be mutagenic in five salmonella typhimurium strains without metabolic activation. additionally, in chinese hamster fibroblast v79 cells, lucidin was found to be mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus, which induced dna single-strand breaks and dna-protein cross-link. in primary rat hepatocytes and transformed c3h/ m2-mouse fibroblasts, it was observed lucidin might induce dna repair synthesis [1].in mouse model, when aci rats were treated with 1-10% madder roots in the diet and control group without madder roots for 780 days, the dose-dependent increase of benign and malignant tumors were observed in liver and kidney. additionally, dna adducts were observed in liver, kidney and colon when treated with 10% madder root for two weeks. the formation of dna adducts and mutagenicity was thought to be associated with lucidin which was contained in the madder roots [2].

References

[1] westendorf j et al. , the genotoxicity of lucidin, a natural component of rubia tinctorum l., and lucidinethylether, a component of ethanolic rubia extracts. cell biol toxicol. 1988, 4(2):225-239.
[2] westendorf j et al. , carcinogenicity and dna adduct formation observed in aci rats after long-term treatment with madder root, rubia tinctorum l. carcinogenesis. 1998, 19(12):2163-2168.

LUCIDIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from LUCIDIN manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Lucidin 478-08-0
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-11-15

Career Henan Chemical Co

Product: LUCIDIN 478-08-0
Price: US $8.00/KG
Min. Order: 1KG
Purity: ＞98% HPLC
Supply Ability: 20 tons
Release date: 2020-02-17

478-08-0, LUCIDINRelated Search:

CARMINE DAMNACANTHOL Carminic Acid Carmine 2-(HYDROXYMETHYL)ANTHRAQUINONE lucidin 3-O-beta-primveroside,Lucidin 3-β-primeveroside LITHIONCARMINE averantin BORAXCARMINE MUNJISTIN averufin lucidin ethyl ether LUCIDIN LITHIUMCARMINE CARMINE MAGNESIUM AMMONIUM CARMINATE dothistromin 1,3,8-TRIHYDROXY-2-(1-HYDROXYHEXYL)-6-METHOXY-9,10-ANTHRACENEDIONE

1,3-dihydroxy-2-(hydroxymethyl)-10-anthracenedione

1,3-dihydroxy-2-hydroxymethylanthraquinoline

1,3-dihydroxy-2-hydroxymethyl-anthraquinon

henine

1,3-DIHYDROXY-2-(HYDROXYMETHYL)ANTHRAQUINONE

LUCIDIN

1,3-Dihydroxy-2-hydroxymethylanthracene-9,10-dione

Lucidin【quinone】

1,3-dihydroxy-2-methylol-9,10-anthraquinone

1,3-Dihydroxy-2-hydroxyMethyl-9,10-anthracenedione, 9CI

HENINE; NSC 30546

CS-1096

Lucidin (NSC 30546)

Lucidin, BR

NSC 30546

9,10-Anthracenedione,1,3-dihydroxy-2-(hydroxymethyl)-

NSC 30546|||Henine

Lucidin-RM

478-08-0

Anthraquinones