Elinzanetant

Product Name: Elinzanetant
CAS No.: 929046-33-3
Chemical Name: Elinzanetant
Synonyms: NT814;NT-814;NT 814;Elinzanetant;Elinzanetant, 10 mM in DMSO;inhibit,BAY3427080,Elinzanetant,BAY-3427080,Inhibitor,Tachykinin receptor,NT-814,NT814,NK receptor,Neurokinin Receptor,NT 814,BAY 3427080;N-{6-[(7S,9aS)-7-(hydroxymethyl)-octahydropyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl}-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide;N-[4-(4-Fluoro-2-methylphenyl)-6-[(7S,9aS)-hexahydro-7-(hydroxymethyl)pyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-3-pyridinyl]-N,α,α-trimethyl-3,5-bis(trifluoromethyl)benzeneacetamide;2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[(7S,9aS)-7-(hydroxymethyl)hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]pyridin-3-yl}-N,2-dimethylpropanamide;Benzeneacetamide, N-[4-(4-fluoro-2-methylphenyl)-6-[(7S,9aS)-hexahydro-7-(hydroxymethyl)pyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-3-pyridinyl]-N,α,α-trimethyl-3,5-bis(trifluoromethyl)-
CBNumber: CB94776711
Molecular Formula: C33H35F7N4O3
Formula Weight: 668.66
MOL File: 929046-33-3.mol

More

Less

Elinzanetant Property

Boiling point:: 672.1±55.0 °C(Predicted)
Density: 1.40±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 100 mg/mL (149.56 mM; Need ultrasonic)
pka: 14.57±0.10(Predicted)
form: Solid
color: White to light yellow
InChIKey: DWRIJNIPBUFCQS-NCTSPAQWNA-N
SMILES: N(C1=CN=C(N2C[C@@]3([H])COCCN3C[C@H]2CO)C=C1C1C=CC(F)=CC=1C)(C)C(=O)C(C1C=C(C(F)(F)F)C=C(C(F)(F)F)C=1)(C)C |&1:7,15,r|

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More

Less

Elinzanetant Chemical Properties,Usage,Production

Uses

Elizanetant (NT-814) is an orally active, selective NK-1,3 receptor antagonist. Elizanetant can reduce the levels of estradiol and progesterone, and is used in the study of vascular motor symptoms and sleep disorders related to menopause in women[1][2][3].

References

[1] Alvaro, Giuseppe; Andreotti, Daniele; Belvedere, Sandro; Di Fabio, Romano; Falchi, Alessandro; Giovannini, Riccardo.Pyridine derivatives as NK receptor inhibitors and their preparation, pharmaceutical compositions, and use in the treatment of psychotic disorders.CN101305011B
[2] Simon JA, et al. Efficacy and safety of elinzanetant, a selective neurokinin-1,3 receptor antagonist for vasomotor symptoms: a dose-finding clinical trial (SWITCH-1). Menopause. 2023 Mar 1;30(3):239-246. DOI:10.1097/GME.0000000000002138
[3] Steve Pawsey, et al. Elinzanetant (NT-814), a Neurokinin 1,3 Receptor Antagonist, Reduces Estradiol and Progesterone in Healthy Women. J Clin Endocrinol Metab. 2021 Jul 13;106(8):e3221-e3234. DOI:10.1210/clinem/dgab108

Elinzanetant Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Elinzanetant Suppliers

China 70 India 2 United States 2 Global 74

Nanjing Vcare PharmaTech Co., Ltd

Tel: 025-58741518 13327700685
Email: sales@vcarepharmatech.com
Country: China
ProdList: 487
Advantage: 58

Taizhou Nanfeng Pharmaceutical Research Institute

Tel: nanfengpharma@126.co 18616377689
Email: nanfengpharma@126.com
Country: China
ProdList: 20009
Advantage: 58

JIANGXI HANHE PHARMACEUTICAL CO.,LTD

Tel: 13122341786
Email: zhiyang.wang@acebright.com
Country: China
ProdList: 121
Advantage: 58

ChengDu TongChuangYuan Pharmaceutical Co.Ltd

Tel: 028-83379370 13880556291
Fax: 028-87747383
Email: tcy@tcypharm.com
Country: China
ProdList: 8556
Advantage: 58

Suzhou Shentuo Pharmaceutical Technology Co., Ltd

Tel: 13911244683 18151949202
Email: info@visonpharma.com
Country: China
ProdList: 491
Advantage: 58

Shijiazhuang Dingmin pharmaceutical Sciences Co.,Ltd

Tel: 0311-67591193 15030197620
Fax: QQ:2786999724
Email: sales02@dingminpharma.com
Country: China
ProdList: 285
Advantage: 58

Nanjing Lebang Pharmaceutical Technology Co., Ltd

Tel: 18860950986
Email: tangmanman@lebangpharma.com
Country: China
ProdList: 739
Advantage: 58

Arizest(Shanghai)Pharmatech Co.,Ltd

Tel: 18109805911
Email: yu.yang@arizest.com
Country: China
ProdList: 519
Advantage: 58

Bayee Biotech (Anqing) Co., Ltd.

Tel: 0556-5032306 18917961636
Email: wtx@bayeebio.com
Country: China
ProdList: 189
Advantage: 61

WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.

Tel: 17702719238 18971495150;
Email: sales@sun-shinechem.com
Country: China
ProdList: 1150
Advantage: 64

More

Less

View Lastest Price from Elinzanetant manufacturers

Shanghai Joiny Pharmaceutical Co.,LTD

Product: N-{6-[(7S,9aS)-7-(hydroxymethyl)-octahydropyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl}-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide 929046-33-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kg
Release date: 2025-11-12

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

Product: Elinzanetant 929046-33-3
Price: US $0.00/g
Min. Order: 1g
Purity: More Than 99%
Supply Ability: 50kg/Month
Release date: 2025-09-09

Shaanxi Dideu New Materials Co. Ltd

Product: N-{6-[(7S,9aS)-7-(hydroxymethyl)-octahydropyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl}-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide 929046-33-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-26

929046-33-3, ElinzanetantRelated Search:

N-{6-[(7S,9aS)-7-(hydroxymethyl)-octahydropyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl}-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide

Benzeneacetamide, N-[4-(4-fluoro-2-methylphenyl)-6-[(7S,9aS)-hexahydro-7-(hydroxymethyl)pyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-3-pyridinyl]-N,α,α-trimethyl-3,5-bis(trifluoromethyl)-

Elinzanetant

NT 814

NT814

NT-814

2-[3,5-bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[(7S,9aS)-7-(hydroxymethyl)hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]pyridin-3-yl}-N,2-dimethylpropanamide

inhibit,BAY3427080,Elinzanetant,BAY-3427080,Inhibitor,Tachykinin receptor,NT-814,NT814,NK receptor,Neurokinin Receptor,NT 814,BAY 3427080

Elinzanetant, 10 mM in DMSO

N-[4-(4-Fluoro-2-methylphenyl)-6-[(7S,9aS)-hexahydro-7-(hydroxymethyl)pyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-3-pyridinyl]-N,α,α-trimethyl-3,5-bis(trifluoromethyl)benzeneacetamide

929046-33-3

C33H35F7N4O3

API