Z-321
- Product Name
- Z-321
- CAS No.
- 130849-58-0
- Chemical Name
- Z-321
- Synonyms
- Z-321;Z321,Z 321;Thiazolidine, 3-[(2,3-dihydro-1H-inden-2-yl)acetyl]-4-(1-pyrrolidinylcarbonyl)-, (4R)- (9CI)
- CBNumber
- CB94796702
- Molecular Formula
- C19H24N2O2S
- Formula Weight
- 344.47
- MOL File
- 130849-58-0.mol
Z-321 Property
- Boiling point:
- 588.8±50.0 °C(Predicted)
- Density
- 1.265±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 250 mg/mL (725.75 mM)
- form
- Solid
- pka
- -0.84±0.20(Predicted)
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- Z450025
- Product name
- Z-321
- Packaging
- 1mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- Z450025
- Product name
- Z-321
- Packaging
- 10mg
- Price
- $1260
- Updated
- 2021/12/16
Z-321 Chemical Properties,Usage,Production
Uses
Z-321, is a prolylendopeptidase (PEP) inhibitor.
in vivo
Z-321 is a prolylendopeptidase (PEP) inhibitor. In the 100 or 200 mg/kg Z-321-treated groups, mean lordosis quotient (LQ) decreases after administration. However, there is no statistical difference among the values before and after. In contrast, the mean LQ in the 300 mg/kg Z-321-treated females is lower than that before injection (P<0.005). Furthermore, when compare to that in the vehicle-treated control group, mean LQ is also significantly lower (p<0.05). The incidence of soliciting behavior decreases after treatment with 300 mg/kg Z-321, when compare to that before treatment, but there is no statistical difference. The present study also demonstrates that 300 mg/kg Z-321 is effective in inhibiting lordosis behavior without disturbance of locomotor activity[1].
Z-321 Preparation Products And Raw materials
Raw materials
Preparation Products
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