ChemicalBook > CAS DataBase List > USL-311

USL-311

Product Name: USL-311
CAS No.: 1373268-67-7
Chemical Name: USL-311
Synonyms: USL-311;USL311, 10 mM in DMSO;6-(4-(1-Isopropylpiperidin-4-yl)-1,4-diazepan-1-yl)-N-(pyridin-4-yl)picolinamide;USL 311,anti-tumor,CXC chemokine receptors,USL311,glioma,inhibit,CXCR,USL-311,Inhibitor;2-Pyridinecarboxamide, 6-[hexahydro-4-[1-(1-methylethyl)-4-piperidinyl]-1H-1,4-diazepin-1-yl]-N-4-pyridinyl-
CBNumber: CB94849040
Molecular Formula: C24H34N6O
Formula Weight: 422.57
MOL File: 1373268-67-7.mol

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USL-311 Property

storage temp.: Store at -20°C
solubility: DMSO : 25 mg/mL (59.16 mM)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0080568
Product name: USL311
Purity: 99.97%
Packaging: 5mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0080568
Product name: USL311
Purity: 99.97%
Packaging: 10mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0080568
Product name: USL311
Purity: 99.97%
Packaging: 50mg
Price: $850
Updated: 2021/12/16

DC Chemicals

Product number: 027674
Product name: USL-311
Packaging: 001
Price: $600
Updated: 2021/12/16

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USL-311 Chemical Properties,Usage,Production

Uses

USL311 is a potent and selective CXCR4 antagonist, with anti-tumor activity. USL311 prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4[1].

IC 50

CXCR4

References

[1] Peter Richardson. Usl-311 for use in the treatment of cancer. WO2018162924A1
[2] Takacs GP, et al. Modulation of the chemokine/chemokine receptor axis as a novel approach for glioma therapy. Pharmacol Ther. 2021 Jun;222:107790. DOI:10.1016/j.pharmthera.2020.107790

USL-311 Preparation Products And Raw materials

Raw materials

Preparation Products

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USL-311 Suppliers

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1373268-67-7, USL-311Related Search:

USL-311

2-Pyridinecarboxamide, 6-[hexahydro-4-[1-(1-methylethyl)-4-piperidinyl]-1H-1,4-diazepin-1-yl]-N-4-pyridinyl-

USL 311,anti-tumor,CXC chemokine receptors,USL311,glioma,inhibit,CXCR,USL-311,Inhibitor

6-(4-(1-Isopropylpiperidin-4-yl)-1,4-diazepan-1-yl)-N-(pyridin-4-yl)picolinamide

USL311, 10 mM in DMSO

1373268-67-7

C24H34N6O