AZOXYMETHANE
- Product Name
- AZOXYMETHANE
- CAS No.
- 25843-45-2
- Chemical Name
- AZOXYMETHANE
- Synonyms
- AOM;AZOXYMETHANE;azoxy-methan;CH3N=N(→O)CH3;Methane, azoxy-;ONN-Azoxydimethane;Dimethyldiazene 1-oxide;Azoxymethane DISCONTINUED;1,2-Dimethyldiazene 1-oxide;(Z)-1,2-diMethyldiazene oxide
- CBNumber
- CB9487512
- Molecular Formula
- C2H6N2O
- Formula Weight
- 74.08
- MOL File
- 25843-45-2.mol
AZOXYMETHANE Property
- Boiling point:
- 97-99 °C (lit.)
- Density
- 0.991 g/mL at 25 °C (lit.)
- refractive index
- 1.4368 (estimate)
- Flash point:
- 24 °C
- storage temp.
- -20°C
- solubility
- Soluble in water, ethanol, and ether
- form
- Liquid
- color
- Oil
- Specific Gravity
- 0.991
- InChI
- InChI=1S/C2H6N2O/c1-3-4(2)5/h1-2H3
- InChIKey
- DGAKHGXRMXWHBX-UHFFFAOYSA-N
- SMILES
- [N+]([O-])(C)=NC
- EPA Substance Registry System
- Azoxymethane (25843-45-2)
Safety
- Hazard Codes
- T
- Risk Statements
- 45-46-10-25-34-36/38
- Safety Statements
- 53-26-36/37/39-45
- RIDADR
- UN 1992 3/PG 3
- WGK Germany
- 3
- RTECS
- PA2975000
- Toxicity
- mma-sat 13,600 mmol/L/20M CNREA8 38,4585,78
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H300Fatal if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H350May cause cancer
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A5486
- Product name
- Azoxymethane
- Purity
- 13.4 M, ≥98%
- Packaging
- 25mg
- Price
- $430
- Updated
- 2024/03/01
- Product number
- A5486
- Product name
- Azoxymethane
- Purity
- 13.4 M, ≥98%
- Packaging
- 100mg
- Price
- $1300
- Updated
- 2024/03/01
- Product number
- FA159673
- Product name
- Azoxymethane
- Packaging
- 5mg
- Price
- $300
- Updated
- 2021/12/16
- Product number
- FA159673
- Product name
- Azoxymethane
- Packaging
- 10mg
- Price
- $400
- Updated
- 2021/12/16
- Product number
- 1463BA
- Product name
- Azoxymethane
- Packaging
- 5mg
- Price
- $455
- Updated
- 2021/12/16
AZOXYMETHANE Chemical Properties,Usage,Production
Uses
Azoxymethane (AOM), a gene mutation agent, may be used with dextran sulfate sodium (DSS) to create cancer models in laboratory animals which can be used to study mechanisms of cancer progression and chemoprevention.
General Description
Clear oily liquid.
Air & Water Reactions
AZOXYMETHANE is sensitive to prolonged exposure to air and elevated temperatures . Soluble in water.
Reactivity Profile
AZOXYMETHANE is an azo compound. Azo, diazo, azido compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides.
Health Hazard
ACUTE/CHRONIC HAZARDS: AZOXYMETHANE is highly flammable and sensitive to elevated temperatures. Upon decomposition it emits toxic fumes.
Fire Hazard
Flash point data for AZOXYMETHANE are not available. AZOXYMETHANE is probably highly flammable.
Biochem/physiol Actions
Carcinogen that induces O6-methylguanine adducts in DNA leading to G→A transitions. Induces tumorigenesis in the colon of laboratory animals and is used to study the mechanism of cancer progression and chemoprevention.
Safety Profile
Suspected carcinogen with experimental carcinogenic and mmorigenic data. Poison by subcutaneous route. An experimental teratogen. Mutation data reported. When heated to decomposition it emits toxic fumes of Nox
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