ChemicalBook > CAS DataBase List > RX 821002
RX 821002
- Product Name
- RX 821002
- CAS No.
- 102575-24-6
- Chemical Name
- RX 821002
- Synonyms
- Rx 821001;RX821002HCl;2-methoxyidazoxan;RX 821002 hydrochlor;2-[2-(2-methoxy-1,4-benzodioanyl)]-imidazoline hydrochloride;2-(3-methoxy-2H-1,4-benzodioxin-3-yl)-4,5-dihydro-1H-imidazole;2-(2,3-Dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole;1H-Imidazole, 2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-
- CBNumber
- CB9498390
- Molecular Formula
- C12H14N2O3
- Formula Weight
- 234.25
- MOL File
- 102575-24-6.mol
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RX 821002 Property
- Boiling point:
- 407.9±45.0 °C(Predicted)
- Density
- 1.34±0.1 g/cm3(Predicted)
- storage temp.
- Desiccate at RT
- pka
- 9.51±0.40(Predicted)
- form
- solid
- color
- white
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RX 821002 Chemical Properties,Usage,Production
Uses
2-Methoxyidazoxan (RX821002) is a compound that modulates play behavior and can increase play behavior in F344 rats, suggesting that it may modulate play behavior by acting on NEα-2 receptors.
Definition
ChEBI: A benzodioxine that is idazoxan substituted at position 2 by a methoxy group.
Biological Activity
Potent, selective α 2 -adrenoceptor antagonist with very low affinity for imidazoline sites. Displays selectivity for the α 2D over the α 2A subtypes (pK d values are 9.7 and 8.2 respectively).
References
[1] Noradrenergic modulation of play in Sprague-Dawley and F344 rats DOI:10.1007/s00213-023-06419-2
RX 821002 Preparation Products And Raw materials
Raw materials
Preparation Products
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RX 821002 Suppliers
- Tel
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- Fax
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- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
- Tel
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- Fax
- --
- info@biotrend.ch
- Country
- Germany
- ProdList
- 1250
- Advantage
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