ChemicalBook > CAS DataBase List > Prothioconazole

Prothioconazole

Product Name: Prothioconazole
CAS No.: 178928-70-6
Chemical Name: Prothioconazole
Synonyms: 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-3H-1,2,4-triazole-3-thione;jau 6476;HSDB7893;HSDB 7893;HSDB-7893;Prothioconzole;PROTHIOCONAZOLE;C sulfur bacteria;Thiazole propionate;Prothioconazole Solution
CBNumber: CB9500604
Molecular Formula: C14H15Cl2N3OS
Formula Weight: 344.26
MOL File: 178928-70-6.mol

Less

Prothioconazole Property

Melting point:: 139.1-144.5°
Boiling point:: 486.7±55.0 °C(Predicted)
Density: 1.50±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 6.9(at 25℃)
form: Solid
color: White to light yellow
InChI: InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)
InChIKey: MNHVNIJQQRJYDH-UHFFFAOYSA-N
SMILES: N1C=NC(=S)N1CC(C1(Cl)CC1)(O)CC1=CC=CC=C1Cl
LogP: 1.770 (est)
EPA Substance Registry System: 3H-1,2,4-Triazole-3-thione, 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro- (178928-70-6)

Less

Safety

Hazard Codes: Xi,N
Risk Statements: 51/53
Safety Statements: 61
RIDADR: UN3077 9/PG 3
WGK Germany: 2
HS Code: 2933998090
Hazardous Substances Data: 178928-70-6(Hazardous Substances Data)
Toxicity: LD50 in rats (mg/kg): > 6200 orally; > 2000 dermally; LC50 in rats (mg/m3): > 4990 by inhalation; LC50 (96 hr) in rainbow trout: 1.83 mg/l (Mauler-Machnik)

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 34232
Product name: Prothioconazole
Purity: PESTANAL
Packaging: 100mg
Price: $279
Updated: 2025/07/31

TRC

Product number: P838830
Product name: Prothioconazole
Packaging: 50mg
Price: $65
Updated: 2021/12/16

TRC

Product number: P838830
Product name: Prothioconazole
Packaging: 1g
Price: $275
Updated: 2021/12/16

AK Scientific

Product number: 3283BB
Product name: Prothioconazole
Packaging: 25g
Price: $197
Updated: 2021/12/16

SynQuest Laboratories

Product number: 8H67-5-27
Product name: 2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-3H-1,2,4-triazole-3-thione
Purity: 95.0%
Packaging: 25g
Price: $240
Updated: 2021/12/16

Less

Prothioconazole Chemical Properties,Usage,Production

Uses

Prothioconazole is an antifungal metabolite used in agricultural fungicides and herbicides.

Definition

ChEBI: 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-1,2,4-triazole-3-thione is a member of the class of triazoles that is 1,2,4-triazole-3-thione substituted at position 2 by a 2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl group. It is a member of monochlorobenzenes, a member of triazoles, a tertiary alcohol, a member of cyclopropanes and a thiocarbonyl compound.

Synthesis

222408-90-4

178928-70-6

The general procedure for the synthesis of 2-(2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1,2,4-triazolidine-3-thione from 2-(2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazolidine-3(2H)-thione was carried out as follows: 2-(1-chlorocyclopropan-1-yl)-1-(2- chlorophenyl)-2-hydroxy-3-(1,2,4-triazolidine-5-thioxo-1-)propane IV (34.6 g, 0.10 mol) was dissolved in acetone (50 mL), followed by slow dropwise addition of hydrogen peroxide (0.15 mmol). The reaction mixture was stirred at 25°C for 2 hours. Upon completion of the reaction, sodium sulfite (6.5 g) was added to the reaction solution and stirring was continued for 1 h at room temperature and the end point of the reaction was detected using potassium iodide starch test paper. Water (50 mL) was added to the reaction system, followed by extraction with ethyl acetate (50 mL each time, three times). The organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product (35 g, 90% purity). The crude product was recrystallized from toluene to give prothioconazole (31.6 g) as a white solid in 98% yield and 90% purity.

References

[1] Patent: CN106986838, 2017, A. Location in patent: Paragraph 0055; 0056; 0057; 0058; 0061

Prothioconazole Preparation Products And Raw materials

Raw materials

Preparation Products

Less

Prothioconazole Suppliers

China 189 France 2 Germany 2 India 6 South Korea 1 Switzerland 1 United Kingdom 2 United States 9 Global 212

Anhui jukai Agrochemical Co., Ltd

Tel: 18019961737
Fax: 0551-65780499
Email: info@jynongye.com
Country: China
ProdList: 22
Advantage: 50

Moltt Biocem Co., Ltd.

Tel: +86-21-38682181 15900741819
Fax: +86-21-38682181
Country: China
ProdList: 282
Advantage: 55

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Shanghai Hekang Biotechnology Co., Ltd.

Tel: 18939837085
Fax: 2880152141(QQ)
Email: youchemicals@gmail.com
Country: China
ProdList: 1839
Advantage: 55

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9637
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15873
Advantage: 55

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

Alta Scientific Co., Ltd.

Tel: 022-6537-8550 15522853686
Fax: 022-2532-9655
Email: sales@altasci.com.cn
Country: China
ProdList: 4511
Advantage: 55

Hubei Kangbaotai Finechem Co., Ltd.

Tel: +86 (27) 8778653
Fax: +86 (27) 8773-8652
Email: 13720228325@163.com
Country: China
ProdList: 337
Advantage: 58

Shanghai Synchem Pharma Co., ltd

Tel: 21-619849051-1 18521059765
Email: synchempharma@aliyun.com
Country: China
ProdList: 6468
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai QianYan Bio-technology Co., Ltd

Tel: 02781293128
Email: orders@biochemsafebuy.com
Country: China
ProdList: 9923
Advantage: 55

parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9595
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Yihe Biological Technology Co., Ltd.

Tel: 021-68882955 17721395025
Fax: 021-68882955
Email: 2423903095@qq.com
Country: China
ProdList: 4991
Advantage: 58

Hubei widely chemical technology Co., Ltd.

Tel: 027-59402396 13419635609
Fax: 027-83989310
Email: 13419635609@163.com
Country: China
ProdList: 1987
Advantage: 55

Wuhan Wsem Biological Co., Ltd.

Tel: 027-83778876 13667159345
Fax: 027-83778876
Email: 13667159345@163.com
Country: China
ProdList: 1997
Advantage: 55

Wellman Pharmaceutical Group Limited

Tel: 027-027-83778875 15807197853
Fax: 027-83991220
Email: 15807197853@163.com
Country: China
ProdList: 3931
Advantage: 58

Shanghai Orgchem Co.,Ltd.

Tel: +86-21-5877 1921
Fax: +86-21-5877 1925
Email: info@chemofchina.com
Country: China
ProdList: 9653
Advantage: 55

JinJin Le Chemical Co., Ltd

Tel: 18001959627(微信同号) 18001959627
Email: jjlchem2@163.com
Country: China
ProdList: 9981
Advantage: 58

Hubei ZhengXingyuan Chemical Co., Ltd.

Tel: 027-87879189 15207106154
Fax: 027-87877281
Email: 3386829764@qq.com
Country: China
ProdList: 309
Advantage: 58

Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-85201366 18938635012
Fax: 0755-85201366
Email: sales@regentsciences.com
Country: China
ProdList: 9751
Advantage: 58

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6039 18920764717
Email: sales@heowns.com
Country: China
ProdList: 23771
Advantage: 60

Suzhou LaiYue Biotechnology Co., Ltd.

Tel: 15161566723 18100692465 1029125529 1029125529@.com
Email: 1029125529@qq.com
Country: China
ProdList: 291
Advantage: 58

Nanjing Maikai Pharmaceutical Technology Co., Ltd.

Tel: 17366198809
Fax: -
Email: mcyy-nj@hotmail.com
Country: China
ProdList: 238
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-63315541 13323832564
Fax: QQ:3001332135
Email: 3001332135@qq.com
Country: China
ProdList: 9972
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Nanjing Zhiyan Technology Co., Ltd.

Tel: 15365097539
Fax: QQ：877997991
Email: 877997991@qq.com
Country: China
ProdList: 1543
Advantage: 58

SHANDONG ZHI SHANG CHEMICAL CO.LTD

Tel: +86 18953170293
Fax: +86 0531-67809011
Email: sales@sdzschem.com
Country: China
ProdList: 2930
Advantage: 58

Finetech Industry Limited

Tel: +86-27-8746-5837 +8619945049750
Fax: 86 27 87772287
Email: info@finetechnology-ind.com
Country: China
ProdList: 9629
Advantage: 58

Hebei Yanxi Chemical Co., Ltd.

Tel: +8618531123677
Email: faithe@yan-xi.com
Country: China
ProdList: 5853
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

Labnetwork lnc.

Tel: +86-27-50766799 +8618062016861
Email: contact@labnetwork.com
Country: China
ProdList: 19987
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20342
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Baoji Guokang Healthchem Co., Ltd.

Tel: +86-0917-3909592 +86-13892490616
Fax: 09173909592
Email: gksales1@gk-bio.com
Country: China
ProdList: 9209
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15115
Advantage: 58

Wuhan Boye Science And Technology Development Co., Ltd.

Tel: 27-81625225 +8615387090420
Fax: 86-27-81625225
Email: sumihu@boyechemicals.com
Country: CHINA
ProdList: 215
Advantage: 58

Win-Win chemical CO., Limited

Tel: +86-0086-577-64498589 +86-15355981851
Fax: 0086-577-56994596
Email: sales@win-winchemical.com
Country: China
ProdList: 14359
Advantage: 58

Longyan Tianhua Biological Technology Co., Ltd

Tel: 0086 18039857276 18039857276
Country: CHINA
ProdList: 2783
Advantage: 58

HUNAN CHEMFISH SCIENTIFIC CO.,LTD

Tel: +86-0731-85567275 13298656710
Fax: QQ:3554193828
Email: sales05@chemfish.com
Country: China
ProdList: 7449
Advantage: 58

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: chemwill_asia@126.com
Country: CHINA
ProdList: 23912
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

Hebei Chuanghai Biotechnology Co., Ltd

Tel: +8615350571055
Fax: whatapp+8619930503282
Email: Sibel@chuanghaibio.com
Country: China
ProdList: 8768
Advantage: 58

Hubei Zhengxingyuan Fine Chemical Co., Ltd.

Tel: 027-027-87879189 15207106154
Fax: 027-87879189
Email: 3386829764@qq.com
Country: China
ProdList: 274
Advantage: 58

Guangdong Wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2886766 13927870850
Fax: 0751-2886756
Email: 3001267247@qq.com
Country: China
ProdList: 9941
Advantage: 58

Hubei xin bonus chemical co. LTD

Tel: 86-13657291602
Fax: 027-59338440
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 22963
Advantage: 58

Less

View Lastest Price from Prothioconazole manufacturers

Qingdao Trust Agri Chemical Co.,Ltd

Product: prothioconazole 178928-70-6
Price: US $0.00/kg
Min. Order: 100kg
Purity: 98
Supply Ability: 100
Release date: 2025-09-28

Hebei Chuanghai Biotechnology Co., Ltd

Product: Prothioconazole 178928-70-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-28

Hebei Chuanghai Biotechnology Co., Ltd

Product: Prothioconazole 178928-70-6
Price: US $30.00-10.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-25

178928-70-6, ProthioconazoleRelated Search:

Mefentrifluconazole Cyproconazol Hexaconazole METCONAZOLE Myclobutanil Difenoconazole IPCONAZOLE IMIBENCONAZOLE Triadimenol TRITICONAZOLE Penconazole Tebuconazole Flutriafol Diniconazole Propiconazole Prochloraz manganese Prothioconazole 3-CHLORO-2-METHYL-2-BUTANOL

2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-3H-1,2,4-triazole-3-thione 95+%

2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-3H-1,2,4-triazole-3-thione

Prothioconazole PESTANAL

3H-1,2,4-Triazole-3-thione, 2-2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl-1,2-dihydro-

jau 6476

prothioconazole (bsi, pa iso)

2-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazole-3(2H)-thione

2-[2-(1-Chloro-cyclopropyl)-3-(2-chlorophenyl)-2-hydroxy-propyl]-1,2-dihydro-3H-1,2,4-Triazol-3-thione

Prothioconazole@100 μg/mL in Acetonitrile

Prothioconazole@1000 μg/mL in Acetonitrile

Prothioconazole Solution

Thiazole propionate

2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2,4-triazole-3-thione

PROTHIOCONAZOLE

C sulfur bacteria

HSDB 7893

HSDB7893

HSDB-7893

Proline 480 SC Fungicide

Prothioconazole in acetonitrile

Prothioconzole

Prothioconazole 10.0 μg/ml Acetonitrile

Prothioconazole 100 μg/ml Acetone

Prothioconazole, 10 mM in DMSO

2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-3H-1,2,4-triazole-3-thione

178928-70-6