ChemicalBook > CAS DataBase List > Bromazine Hydrochloride

Bromazine Hydrochloride

Product Name: Bromazine Hydrochloride
CAS No.: 1808-12-4
Chemical Name: Bromazine Hydrochloride
Synonyms: deserol;bromazin;Cetirizine-d;Bromazine HCl;bromo-benzdryl;EINECS 204-238-8;ambodrylhydrochloride;bromazine hydrochloride;Bromodiphenhydramine HCl;DIPHENHYDRAMINE EP IMP C
CBNumber: CB9501636
Molecular Formula: C17H21BrClNO
Formula Weight: 370.71174
MOL File: 1808-12-4.mol

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Bromazine Hydrochloride Property

Melting point:: 144-145°
storage temp.: Refrigerator
solubility: Acetone (Slightly), Methanol (Slightly), Water (Slightly)
form: Solid
color: Pale Yellow
BRN: 3754363
InChI: InChI=1S/C17H20BrNO.ClH/c1-19(2)12-13-20-17(14-6-4-3-5-7-14)15-8-10-16(18)11-9-15;/h3-11,17H,12-13H2,1-2H3;1H
InChIKey: ZQDJSWUEGOYDGT-UHFFFAOYSA-N
SMILES: C(OCCN(C)C)(C1=CC=CC=C1)C1=CC=C(Br)C=C1.Cl

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Safety

HS Code: 2922190900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1077005
Product name: Bromodiphenhydramine hydrochloride
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200mg
Price: $538
Updated: 2025/07/31

Sigma-Aldrich

Product number: PHR1861
Product name: Bromodiphenhydramine Hydrochloride
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 50mg
Price: $540
Updated: 2022/05/15

Cayman Chemical

Product number: 29636
Product name: Bromodiphenhydramine (hydrochloride)
Packaging: 5mg
Price: $51
Updated: 2024/03/01

Cayman Chemical

Product number: 29636
Product name: Bromodiphenhydramine (hydrochloride)
Packaging: 10mg
Price: $92
Updated: 2024/03/01

Cayman Chemical

Product number: 29636
Product name: Bromodiphenhydramine (hydrochloride)
Packaging: 25mg
Price: $165
Updated: 2024/03/01

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Bromazine Hydrochloride Chemical Properties,Usage,Production

Description

Bromodiphenhydramine is a histamine H₁ receptor antagonist. It induces histamine release in isolated guinea pig lung when used at a concentration of 1 mM but completely prevents ovalbumin-induced histamine release in lungs isolated from ovalbumin-sensitized guinea pigs when used at concentrations of 100 and 200 μg/ml. Bromodiphenhydramine (17 mg/kg) inhibits formalin-induced paw edema in rats. It increases survival in a mouse model of systemic S. typhimurium infection when administered at doses of 1.5 and 3 mg/kg.

Uses

Antihistaminic.

Definition

ChEBI: The hydrochloride salt of bromazine. An antihistamine with antimicrobial properties, it is used in the control of cutaneous allergies.

brand name

Ambodryl.

General Description

Bromodiphenhydraminehydrochloride, 2-[(4-bromophenyl)-phenylmethoxy]-N, N-dimethylethanamine hydrochloride(Ambodryl Hydrochloride), is a white to pale buff crystallinepowder that is freely soluble in water and in alcohol.Relative to diphenhydramine, bromodiphenhydramine ismore lipid soluble and was twice as effective in protectingagainst the lethal effects of histamine aerosols.

References

[1] ABBAS AHMADI. Synthesis and anti-inflammatory effects of new piperazine and ethanolamine derivatives of H(1)-antihistaminic drugs.[J]. Mini reviews in medicinal chemistry, 2012, 12 12: 1282-1292. DOI: 10.2174/138955712802762013
[2] I. MOTA W. D D S. THE ANTI-ANAPHYLACTIC AND HISTAMINE-RELEASING PROPERTIES OF THE ANTIHISTAMINES. THEIR EFFECT ON THE MAST CELLS[J]. British Journal of Pharmacology, 1960, 15 3: 396-404. DOI: 10.1111/j.1476-5381.1960.tb01262.x
[3] SUJATA G. DASTIDAR. Antibacterial Activity of Ambodryl and Benadryl[J]. Journal of Applied Microbiology, 1976, 41 2: 209-214. DOI: 10.1111/j.1365-2672.1976.tb00621.x

Bromazine Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1808-12-4, Bromazine HydrochlorideRelated Search:

Bromazine Hydrochloride 1-(4-Bromophenyl)ethanol embramine hydrochloride N-2-(4-bromobenzhydryloxy)ethyldimethylamine 4-BROMOBENZHYDROL

Diphenhydramine Impurity C HCl (Bromazine Hydrochloride)

Bromodiphenhydramine HCl

Diphenhydramine Impurity 3（Diphenhydramine EP Impurity C）

2-((4-bromophenyl)phenylmethoxy)-n,n-dimethyl-ethanaminhydrochloride

2-((p-bromo-alpha-phenylbenzyl)oxy)-n,n-dimethylethylaminehydrochloride

2-((p-bromo-alpha-phenylbenzyl)oxy)-n,n-dimethyl-ethylaminhydrochloride

2-(4-bromobenzohydryloxy)-ethyl-dimethylaminehydrochloride

2-(4-bromodiphenylmethoxy)ethyldimethylamine

4-bromo-alpha-phenylbenzyl2-dimethylaminoethylether

ambodrylhydrochloride

beta-(p-bromobenzhydryloxy)ethyldimethylaminehydrochloride

BROMODIPHENHYDRAMINE HYDROCHLORIDE (200 MG)

bromazin

bromdiphenylhydraminehydrochloride

bromo-benzdryl

bromodiphenhydraminehydrochloride

deserol

bromazine hydrochloride

2-[(4-bromophenyl)phenylmethoxy]ethyl(dimethyl)ammonium chloride

EINECS 204-238-8

2-(4-BroModiphenylMethoxy)ethyldiMethylaMine Hydrochloride

2-[(4-BroMophenyl)phenylMethoxy]-N,N-diMethylethanaMine Hydrochloride

2-[(p-BroMo-α-phenylbenzyl)oxy]-N,N-diMethylethylaMine Hydrochloride

IMp. H (EP) as Hydrochloride: 2-[(RS)-(4- BroMophenyl)(phenyl)Methoxy]-N,N-diMethyl- ethanaMine Hydrochloride (4-BroModiphen- hydraMine Hydrochloride

Diphenhydramine EP Impurity C HCl

Diphenhydramine Impurity C hydrochloride

Bromazine HCl

Bromodiphenhydramine Hydrochloride (1077005)

bacteria,inhibit,Inhibitor,antihistamine,Salmonella typhimurium,Histamine Receptor,Bromodiphenhydramine,Bromodiphenhydramine hydrochloride,cutaneous allergies,Bacterial,Ambodryl

Diphenhydramine Hydrochloride Impurity C as Hydrochloride

Diphenhydramine Impurity 3 (Diphenhydramine EP Impurity C HCl)

Dimenhydrinate Impurity H as Hydrochloride

Diphenhydramine Hydrochloride EP Impurity C as Hydrochloride

Dimenhydrinate EP Impurity H as Hydrochloride

Cetirizine-d

DIPHENHYDRAMINE EP IMP C

Dimenhydrinate EP Impurity H HCl (Diphenhydramine EP Impurity C HCl)

Diphenhydramine hydrochloride EP Impurity C

Bromodiphenhydramine hydrochloride, 10 mM in DMSO

2-[(RS)-(4-Bromophenyl)phenylmethoxy]-N,N-dimethylethanamine hydrochloride

Bromazine Hydrochloride 1.0 mg/ml in Methanol (as free base)

1808-12-4

C17H21BrClNO

Amines

Aromatics

Intermediates & Fine Chemicals

Pharmaceuticals