ChemicalBook > CAS DataBase List > 4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

Product Name: 4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
CAS No.: 2093536-12-8
Chemical Name: 4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Synonyms: SY2-062;Thalidomide-4-Br;Thalidomide 4-Bromine;4-bromo-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione;4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;1H-Isoindole-1,3(2H)-dione, 4-bromo-2-(2,6-dioxo-3-piperidinyl)-;4-bromo-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione - [B84706];4Bromo2(2,6dioxopiperidin3yl)isoindoline1,3dione,4 Bromo 2 (2,6 dioxopiperidin 3 yl)isoindoline 1,3 dione
CBNumber: CB95423364
Molecular Formula: C13H9BrN2O4
Formula Weight: 337.13
MOL File: 2093536-12-8.mol

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4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Property

Boiling point:: 565.4±45.0 °C(Predicted)
Density: 1.794±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
pka: 10?+-.0.40(Predicted)
form: Solid
color: Off-white to gray
InChI: InChI=1S/C13H9BrN2O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5H2,(H,15,17,18)
InChIKey: NUICQRZENMKDBW-UHFFFAOYSA-N
SMILES: C1(=O)C2=C(C(Br)=CC=C2)C(=O)N1C1CCC(=O)NC1=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: B6527
Product name: 4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Packaging: 1G
Price: $147
Updated: 2025/07/31

TCI Chemical

Product number: B6527
Product name: 4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Packaging: 5G
Price: $501
Updated: 2025/07/31

Abosyn

Product number: 10-3503
Product name: 4-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Purity: 95%-98%
Packaging: 1g
Price: $1200
Updated: 2021/12/16

Ambeed

Product number: A1215363
Product name: 4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Purity: 98%
Packaging: 5g
Price: $199
Updated: 2021/12/16

Acrotein

Product number: H-7886
Product name: 4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Purity: 97%
Packaging: 1g
Price: $385
Updated: 2021/12/16

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4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Chemical Properties,Usage,Production

Description

4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione is a thalidomide analog that can be useful in PROTAC research.

Uses

Thalidomide-4-Br (compound 53) is a compound with a bromodomain. Thalidomide-4-Br can be used in the research of inflammation, tumor and neurology[1].

References

[1] Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018 Jan 25;61(2):462-481. DOI:10.1021/acs.jmedchem.6b01816

4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Suppliers

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2093536-12-8, 4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioneRelated Search:

4-Bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

1H-Isoindole-1,3(2H)-dione, 4-bromo-2-(2,6-dioxo-3-piperidinyl)-

4Bromo2(2,6dioxopiperidin3yl)isoindoline1,3dione,4 Bromo 2 (2,6 dioxopiperidin 3 yl)isoindoline 1,3 dione

SY2-062

4-bromo-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione

Thalidomide 4-Bromine

Thalidomide-4-Br

4-bromo-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione - [B84706]

2093536-12-8