ChemicalBook > CAS DataBase List > LY-3381916

LY-3381916

Product Name
LY-3381916
CAS No.
2166616-75-5
Chemical Name
LY-3381916
Synonyms
LY-3381916;LY3381916 (IDO1-IN-5);IDO1-IN-5, 10 mM in DMSO;Indoleamine 2,3-Dioxygenase (IDO),IDO1IN5,inhibit,Inhibitor,IDO-1-IN-5,IDO1 IN 5;4-fluoro-N-{(1R)-1-[1-(tetrahydro-2H-pyran-4-ylcarbonyl)-2,3-dihydro-1H-indol-5-yl]ethyl}benzamide;Benzamide, N-[(1R)-1-[2,3-dihydro-1-[(tetrahydro-2H-pyran-4-yl)carbonyl]-1H-indol-5-yl]ethyl]-4-fluoro-
CBNumber
CB95477387
Molecular Formula
C23H25FN2O3
Formula Weight
396.45
MOL File
2166616-75-5.mol
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LY-3381916 Property

Boiling point:
665.5±55.0 °C(Predicted)
Density 
1.251±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml
form 
A crystalline solid
pka
13.93±0.46(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0087014
Product name
IDO1-IN-5
Purity
98.58%
Packaging
5mg
Price
$90
Updated
2021/12/16
ChemScene
Product number
CS-0087014
Product name
IDO1-IN-5
Purity
98.58%
Packaging
10mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-0087014
Product name
IDO1-IN-5
Purity
98.58%
Packaging
25mg
Price
$250
Updated
2021/12/16
ChemScene
Product number
CS-0087014
Product name
IDO1-IN-5
Purity
98.58%
Packaging
50mg
Price
$400
Updated
2021/12/16
ChemScene
Product number
CS-0087014
Product name
IDO1-IN-5
Purity
98.58%
Packaging
100mg
Price
$625
Updated
2021/12/16
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LY-3381916 Chemical Properties,Usage,Production

Uses

LY-3381916 (IDO1-IN-5) is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1].

IC 50

IDO1

References

[1] Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78(13).

LY-3381916 Preparation Products And Raw materials

Raw materials

Preparation Products

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LY-3381916 Suppliers

Chembest Research Laboratories Limited
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2166616-75-5, LY-3381916Related Search:


  • LY-3381916
  • Benzamide, N-[(1R)-1-[2,3-dihydro-1-[(tetrahydro-2H-pyran-4-yl)carbonyl]-1H-indol-5-yl]ethyl]-4-fluoro-
  • LY3381916 (IDO1-IN-5)
  • Indoleamine 2,3-Dioxygenase (IDO),IDO1IN5,inhibit,Inhibitor,IDO-1-IN-5,IDO1 IN 5
  • 4-fluoro-N-{(1R)-1-[1-(tetrahydro-2H-pyran-4-ylcarbonyl)-2,3-dihydro-1H-indol-5-yl]ethyl}benzamide
  • IDO1-IN-5, 10 mM in DMSO
  • 2166616-75-5