ChemicalBook > CAS DataBase List > LY-3381916
LY-3381916
- Product Name
- LY-3381916
- CAS No.
- 2166616-75-5
- Chemical Name
- LY-3381916
- Synonyms
- LY-3381916;LY3381916 (IDO1-IN-5);IDO1-IN-5, 10 mM in DMSO;Indoleamine 2,3-Dioxygenase (IDO),IDO1IN5,inhibit,Inhibitor,IDO-1-IN-5,IDO1 IN 5;4-fluoro-N-{(1R)-1-[1-(tetrahydro-2H-pyran-4-ylcarbonyl)-2,3-dihydro-1H-indol-5-yl]ethyl}benzamide;Benzamide, N-[(1R)-1-[2,3-dihydro-1-[(tetrahydro-2H-pyran-4-yl)carbonyl]-1H-indol-5-yl]ethyl]-4-fluoro-
- CBNumber
- CB95477387
- Molecular Formula
- C23H25FN2O3
- Formula Weight
- 396.45
- MOL File
- 2166616-75-5.mol
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LY-3381916 Property
- Boiling point:
- 665.5±55.0 °C(Predicted)
- Density
- 1.251±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml
- form
- A crystalline solid
- pka
- 13.93±0.46(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0087014
- Product name
- IDO1-IN-5
- Purity
- 98.58%
- Packaging
- 5mg
- Price
- $90
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0087014
- Product name
- IDO1-IN-5
- Purity
- 98.58%
- Packaging
- 10mg
- Price
- $150
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0087014
- Product name
- IDO1-IN-5
- Purity
- 98.58%
- Packaging
- 25mg
- Price
- $250
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0087014
- Product name
- IDO1-IN-5
- Purity
- 98.58%
- Packaging
- 50mg
- Price
- $400
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0087014
- Product name
- IDO1-IN-5
- Purity
- 98.58%
- Packaging
- 100mg
- Price
- $625
- Updated
- 2021/12/16
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LY-3381916 Chemical Properties,Usage,Production
Uses
LY-3381916 (IDO1-IN-5) is a potent, selective and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1].
IC 50
IDO1
References
[1] Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78(13).
LY-3381916 Preparation Products And Raw materials
Raw materials
Preparation Products
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LY-3381916 Suppliers
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