Nicergoline EP Impurity G

Product Name: Nicergoline EP Impurity G
CAS No.: 57935-65-6
Chemical Name: Nicergoline EP Impurity G
Synonyms: Dihydroniergoline;Nicergoline EP Impurity 9;Nicergoline EP Impurity G;8b-(5-Bromonicotinoyloxymethyl)-1,6-dimethyl-10a-ergoline;Ergoline-8-methanol, 1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)-;((6aR,9R,10aR)-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate;(6aR,9R,10aR)-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]methyl 5-bromopyridine-3-carboxylate
CBNumber: CB95479578
Molecular Formula: C23H24BrN3O2
Formula Weight: 454.37
MOL File: 57935-65-6.mol

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Nicergoline EP Impurity G Property

Boiling point:: 583.8±45.0 °C(Predicted)
Density: 1.50±0.1 g/cm3(Predicted)
pka: 7.56±0.20(Predicted)
InChIKey: JSOSQCRIXCEVRN-FXKZQFCGNA-N
SMILES: CN1C=C2C[C@@]3([H])N(C[C@H](COC(C4=CN=CC(Br)=C4)=O)C[C@]3([H])C3C=CC=C1C2=3)C |&1:5,9,22,r|

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Hazard and Precautionary Statements (GHS)

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Nicergoline EP Impurity G Chemical Properties,Usage,Production

Uses

10-Demethoxy Nicergoline is an impurity of Nicergoline (N394550) which is a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia. Nicergoline has shown to protect cultured neurons against β-amyloid toxicity. Nicergoline protects against neuronal cell death induced by activated microglia and astrocytes through the inhibition of inflammatory mediators and the upregulation of neurotrophic factors by glial cells. Nicergoline is a drug used for age-dependent cognitive impairment and it protects cultured neurons against β-amyloid toxicity.

Nicergoline EP Impurity G Preparation Products And Raw materials

Raw materials

Preparation Products

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Nicergoline EP Impurity G Suppliers

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57935-65-6, Nicergoline EP Impurity GRelated Search:

Nicergoline EP Impurity G

Ergoline-8-methanol, 1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)-

8b-(5-Bromonicotinoyloxymethyl)-1,6-dimethyl-10a-ergoline

((6aR,9R,10aR)-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl 5-bromonicotinate

(6aR,9R,10aR)-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]methyl 5-bromopyridine-3-carboxylate

Dihydroniergoline

Nicergoline EP Impurity 9

57935-65-6