BPK-29 hydrochloride

Product Name: BPK-29 hydrochloride
CAS No.: 2444815-73-8
Chemical Name: BPK-29 hydrochloride
Synonyms: BPK-29 hcl;BPK-29 hydrochloride;BPK-29 hydrochloride, 10 mM in DMSO;inhibit,BPK 29,BPK29,BPK-29,Inhibitor,BPK 29 hydrochloride,BPK29 hydrochloride
CBNumber: CB95559122
Molecular Formula: C26H33Cl2N3O3
Formula Weight: 506.47
MOL File: 2444815-73-8.mol

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BPK-29 hydrochloride Property

storage temp.: Store at -20°C
solubility: DMSO: 62.5 mg/mL (123.41 mM)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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BPK-29 hydrochloride Chemical Properties,Usage,Production

Description

BPK-29 hydrochloride is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein (such RBM45 and SNW1) interactions by covalently modifying C274. BPK-29 hydrochloride impairs the anchorage-independent growth of KEAP1-mutant cancer cells[1].

BPK-29 hydrochloride substantially engages NR0B1 with good overall proteomic selectivity in KEAP1-mutant Non-Small Cell Lung Cancers[1].

References

[1]. Bar-Peled L, et al. Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer. Cell. 2017 Oct 19;171(3):696-709.e23.

BPK-29 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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BPK-29 hydrochloride Suppliers

China 8 United States 2 Global 10

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
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TargetMol Chemicals Inc.

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Shanghai Yifei Biotechnology Co. , Ltd.

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https://hanhongsci.com/

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Absin Bioscience Inc.

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Proteintech China

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Shanghai Hao Zhun Biological Technology Co., Ltd.

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2444815-73-8, BPK-29 hydrochlorideRelated Search:

BPK-29 hydrochloride

BPK-29 hcl

inhibit,BPK 29,BPK29,BPK-29,Inhibitor,BPK 29 hydrochloride,BPK29 hydrochloride

BPK-29 hydrochloride, 10 mM in DMSO

2444815-73-8