MYCi975
- Product Name
- MYCi975
- CAS No.
- 2289691-01-4
- Chemical Name
- MYCi975
- Synonyms
- MYCi975;NUCC-0200975;MYCi975 ,S8906;MYCi-975,MYCi975;MYCi975 (NUCC-0200975);MYCi975, 10 mM in DMSO;4’-Chloro-6-[(4-chlorobenzyl)oxy]-3-[1-methyl-3-(trifluoromethyl)-5-pyrazolyl]-3’-(trifluoromethyl)-[1,1’-biphenyl]-2-ol;4’-Chloro-6-[(4-chlorobenzyl)oxy]-3-[1-methyl-3-(trifluoromethyl)-5-pyrazolyl]-3’-(trifluoromethyl)-[1,1’-biphenyl]-2-ol;4'-Chloro-6-((4-chlorobenzyl)oxy)-3-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)-3'-(trifluoromethyl)-[1,1'-biphenyl]-2-ol;[1,1'-Biphenyl]-2-ol, 4'-chloro-6-[(4-chlorophenyl)methoxy]-3-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]-3'-(trifluoromethyl)-
- CBNumber
- CB95821225
- Molecular Formula
- C25H16Cl2F6N2O2
- Formula Weight
- 561.3
- MOL File
- 2289691-01-4.mol
MYCi975 Property
- Boiling point:
- 566.5±50.0 °C(Predicted)
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO:56.0(Max Conc. mg/mL);99.8(Max Conc. mM)
- pka
- 7.99±0.50(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- Axon3229
- Product name
- MYCi975-NUCC-0200975
- Purity
- 99%
- Packaging
- 2x5mg
- Price
- $176
- Updated
- 2021/12/16
- Product number
- DC32580
- Product name
- MYCi975
- Packaging
- 100mg
- Price
- $700
- Updated
- 2021/12/16
MYCi975 Chemical Properties,Usage,Production
Description
MYCi975 is an inhibitor of the protein-protein interaction between Myc and Myc-associated factor X (MAX).1 It binds to Myc (Kd = 2.75 µM) and increases GSK3β-mediated Myc phosphorylation in a cell-free assay. MYCi975 (5 and 10 µM) decreases the viability of MyC-CaP and LNCaP prostate cancer cells. It induces apoptosis in a panel of 11 breast cancer cell lines when used at a concentration of 10 µM.2 In vivo, MYCi975 (100 mg/kg) reduces tumor volume in a MyC-CaP mouse xenograft model.WARNING This product is not for human or veterinary use.
MYCi975 Preparation Products And Raw materials
Raw materials
Preparation Products
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