E)-1-(4-Hydroxy-phenyl)-3-(2,4,6-trimethoxy-phenyl)-propenone
- Product Name
- E)-1-(4-Hydroxy-phenyl)-3-(2,4,6-trimethoxy-phenyl)-propenone
- CAS No.
- 1389310-69-3
- Chemical Name
- E)-1-(4-Hydroxy-phenyl)-3-(2,4,6-trimethoxy-phenyl)-propenone
- Synonyms
- NorA-IN-1;2,4,6-Trimethoxy-4'-hydroxychalcone;2,4,6-Trimethoxy-4'-hydroxychalcone;E)-1-(4-Hydroxy-phenyl)-3-(2,4,6-trimethoxy-phenyl)-propenone;1-(4-Hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one;2-Propen-1-one, 1-(4-hydroxyphenyl)-3-(2,4,6-trimethoxyphenyl)-
- CBNumber
- CB96187166
- Molecular Formula
- C18H18O5
- Formula Weight
- 314.33
- MOL File
- 1389310-69-3.mol
E)-1-(4-Hydroxy-phenyl)-3-(2,4,6-trimethoxy-phenyl)-propenone Property
- Boiling point:
- 529.9±50.0 °C(Predicted)
- Density
- 1+-.0.06 g/cm3(Predicted)
- form
- Solid
- pka
- 7.51±0.15(Predicted)
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
E)-1-(4-Hydroxy-phenyl)-3-(2,4,6-trimethoxy-phenyl)-propenone Chemical Properties,Usage,Production
Uses
NorA-IN-1 (Compound 16) is a NorA inhibitor. NorA-IN-1 inhibits NorA efflux pump in everted membrane vesicles. NorA-IN-1 can be used for research of multidrug resistance[1].
References
[1] Holler JG, et al. Chalcone inhibitors of the NorA efflux pump in Staphylococcus aureus whole cells and enriched everted membrane vesicles. Bioorg Med Chem. 2012 Jul 15;20(14):4514-21. DOI:10.1016/j.bmc.2012.05.025
E)-1-(4-Hydroxy-phenyl)-3-(2,4,6-trimethoxy-phenyl)-propenone Preparation Products And Raw materials
Raw materials
Preparation Products
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