1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one

Product Name: 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one
CAS No.: 16616-39-0
Chemical Name: 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one
Synonyms: MLS-532223;MLS000532223;MLS000532223, 10 mM in DMSO;1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one;1-(3-Nitrophenyl)-3-phenylprop-2-yn-1-one;2-Propyn-1-one, 1-(3-nitrophenyl)-3-phenyl-;GTPases,Inhibitor,MLS-000532223,MLS 000532223,MLS000532223,Rab,cytoskeleton,actin,Rho GTPases,Ras,inhibit
CBNumber: CB96188330
Molecular Formula: C15H9NO3
Formula Weight: 251.24
MOL File: 16616-39-0.mol

More

Less

1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one Property

Melting point:: 120-121 °C
Boiling point:: 419.6±47.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
storage temp.: RT (des.)
solubility: Soluble in DMSO (up to 20 mg/ml).
form: solid
color: Beige
Stability:: Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-0064006
Product name: MLS000532223
Purity: 99.47%
Packaging: 5mg
Price: $400
Updated: 2021/12/16

ChemScene

Product number: CS-0064006
Product name: MLS000532223
Purity: 99.47%
Packaging: 10mg
Price: $600
Updated: 2021/12/16

ChemScene

Product number: CS-0064006
Product name: MLS000532223
Purity: 99.47%
Packaging: 50mg
Price: $1800
Updated: 2021/12/16

CSNpharm

Product number: CSN27587
Product name: MLS000532223
Packaging: 5mg
Price: $372
Updated: 2021/12/16

CSNpharm

Product number: CSN27587
Product name: MLS000532223
Packaging: 50mg
Price: $1674
Updated: 2021/12/16

More

Less

1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one Chemical Properties,Usage,Production

Description

MLS-532223 (16616-39-0) is a high-affinity selective inhibitor of Rho family GTPases (EC50=10 μM). It inhibits EGF-stimulated Rac1 activation (3-10 μM). Cell permeable.

Uses

MLS000532223 is a high affinity, selective inhibitor of Rho family GTPases, with EC50 values ranging from 16 μM to 120 μM. MLS000532223 prevents GTP binding to several GTPases[1].

Definition

ChEBI: 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one is an aromatic compound.

References

[1] ZURAB SURVILADZE . Identification of a Small GTPase Inhibitor Using a High-Throughput Flow Cytometry Bead-Based Multiplex Assay[J]. SLAS Discovery, 2010, 15 1: Pages 10-20. DOI:10.1177/1087057109352240

1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one Suppliers

China 25 United States 4 Global 29

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 8011
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Shandong Jirun Biomedical Technology Co., Ltd.

Tel: 0539-0539-8613587 17661611089
Fax: qq2639273505
Email: 2639273505@qq.com
Country: China
ProdList: 207
Advantage: 58

Hefei Mokai Pharmaceutical Technology Co., Ltd

Tel: 18130062233
Email: 3362556465@qq.com
Country: China
ProdList: 8100
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-55013243 15324716602
Email: 2853979810@qq.com
Country: China
ProdList: 9898
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50751
Advantage: 58

Sichuan Shangang Biopharmaceutical Technology Co., Ltd

Tel: 13990000934,13076045191 13990000934
Email: 7109671@qq.com
Country: China
ProdList: 265
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-025-66113011 18626450290
Email: cb5@aikonchem.com
Country: China
ProdList: 10358
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: 400-6206333 13167063860
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 48457
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Adooq Bioscience LLC

Tel: 400-025-6535
Email: sales@adooq.cn
Country: China
ProdList: 6215
Advantage: 58

Selleck Chemicals

Tel: 400-668-6834
Email: info@selleck.cn
Country: China
ProdList: 6071
Advantage: 58

Compound Net Biotechnology Inc.

Tel: +8615303909093
Email: sales@compound-net.com
Country: China
ProdList: 2914
Advantage: 58

Guangzhou Keyu Biotechnology Co., Ltd.

Tel: 18818657868
Country: CHINA
ProdList: 0
Advantage: 58

Guangzhou Huiheng Biotechnology Co., Ltd.

Tel: 18675945663
Country: CHINA
ProdList: 126
Advantage: 58

Guangzhou Squirrel Biotechnology Co., Ltd.

Tel: 17765276361
Country: CHINA
ProdList: 109
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6208
Advantage: 58

Proteintech China

Tel: --
Fax: --
Email: Proteintech-CN@ptglab.com
Country: CHINA
ProdList: 6290
Advantage: 58

16616-39-0, 1-(3-nitrophenyl)-3-phenyl-2-propyn-1-oneRelated Search:

3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone NOCODAZOLE 2-Benzofurancarboxamide, N-[3-chloro-4-[4-(2-methyl-1-oxopropyl)-1-piperazinyl]phenyl]- Dynasore

1-(3-nitrophenyl)-3-phenyl-2-propyn-1-one

MLS000532223

2-Propyn-1-one, 1-(3-nitrophenyl)-3-phenyl-

1-(3-Nitrophenyl)-3-phenylprop-2-yn-1-one

MLS-532223

GTPases,Inhibitor,MLS-000532223,MLS 000532223,MLS000532223,Rab,cytoskeleton,actin,Rho GTPases,Ras,inhibit

MLS000532223, 10 mM in DMSO

16616-39-0