ChemicalBook > CAS DataBase List > 7-Azaindole-5-carboxaldehyde

7-Azaindole-5-carboxaldehyde

Product Name
7-Azaindole-5-carboxaldehyde
CAS No.
849067-90-9
Chemical Name
7-Azaindole-5-carboxaldehyde
Synonyms
1H-PYRROLO[2,3-B]PYRIDINE-5-CARBALDEHYDE;7-Azaindole-5-carbaldehyde;7-AZAINDOLE-5-CARBOXALDEHYDE;7-Azaindole-5-carbaldehyd...;1H-Pyrrolo[2,3-b]pyridin-5-carbaldehyd;1H-Pyrrolo[2,3-b]pyridin-5-carbaldehyde;1H-Pyrrolo[2,3-b]pyridine-5-carboxaldehyde;1H-Pyrrolo[2,3-b]pyridine-5-carboxaldehyde (9CI, ACI);7-Azaindole-5-carboxaldehyde1H-Pyrrolo[2,3-b]pyridine-5-carbaldehyde
CBNumber
CB9684913
Molecular Formula
C8H6N2O
Formula Weight
146.15
MOL File
849067-90-9.mol
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7-Azaindole-5-carboxaldehyde Property

Melting point:
181-182°C
Density 
1.368±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
pka
13.02±0.40(Predicted)
Appearance
Light yellow to yellow Solid
InChI
InChI=1S/C8H6N2O/c11-5-6-3-7-1-2-9-8(7)10-4-6/h1-5H,(H,9,10)
InChIKey
HDANOCTXZFZIHB-UHFFFAOYSA-N
SMILES
C12NC=CC1=CC(C=O)=CN=2
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
ADE000887
Product name
1H-Pyrrolo[2,3-b]pyridine-5-carbaldehyde
Purity
Aldrich
Packaging
1g
Price
$795
Updated
2023/01/07
TRC
Product number
B530395
Product name
1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde
Packaging
100mg
Price
$90
Updated
2021/12/16
Apolloscientific
Product number
OR308040
Product name
1H-Pyrrolo[2,3-b]pyridine-5-carbaldehyde
Packaging
1g
Price
$720
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-1-079
Product name
7-Azaindole-5-carbaldehyde
Packaging
1g
Price
$749
Updated
2021/12/16
Matrix Scientific
Product number
021142
Product name
1H-Pyrrolo[2,3-b]pyridine-5-carbaldehyde
Purity
98%
Packaging
500mg
Price
$132
Updated
2021/12/16
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7-Azaindole-5-carboxaldehyde Chemical Properties,Usage,Production

Synthesis

68-12-2

183208-35-7

849067-90-9

The general procedure for the synthesis of 7-azaindole-5-carbaldehyde from N,N-dimethylformamide and 5-bromo-7-azaindole was as follows: to an anhydrous THF solution (50 mL) of 5-bromo-1H-pyrrolo[2,3-b]pyridine (1.0 g, 5.0 mmol, 1.0 eq.) was slowly added, under protection of argon, at -78 °C a hexane solution of 1.6 M n-butyllithium (6.7 mL, 10.7 mmol, 2.1 eq.). The reaction mixture was stirred at -78 °C for 40 min. Subsequently, 1 mL of anhydrous DMF was added to the resulting suspension and the reaction mixture was continued to be stirred overnight at room temperature. Upon completion of the reaction, the reaction mixture was quenched with saturated NH4Cl solution. The organic layer was separated and the aqueous phase was extracted with EtOAc. The organic layers were combined, washed with brine, dried over Na2SO4, filtered and concentrated to afford 1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde (Intermediate 3a) as a yellow solid (1.0 g; yield: 69%; UPLC purity: 98%).

References

[1] Patent: US2018/179199, 2018, A1. Location in patent: Paragraph 0459-0460
[2] Patent: WO2016/114816, 2016, A1. Location in patent: Paragraph 0300

7-Azaindole-5-carboxaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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7-Azaindole-5-carboxaldehyde Suppliers

Aladdin Scientific
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tp@aladdinsci.com
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United States
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Synthonix Inc
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Combi-Blocks Inc.
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SynQuest Laboratories, Inc.
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Riedel-de Haen AG
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Matrix Scientific
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Sinova Inc.
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Adesis, Inc.
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View Lastest Price from 7-Azaindole-5-carboxaldehyde manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
1H-Pyrrolo[2,3-b]pyridin-5-carbaldehyd 849067-90-9
Price
US $1.60-6.60/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-19
Career Henan Chemical Co
Product
1H-PYRROLO[2,3-B]PYRIDINE-5-CARBALDEHYDE 849067-90-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-25

849067-90-9, 7-Azaindole-5-carboxaldehydeRelated Search:


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  • 849067-90-9
  • C8H5N2O