DYNAMIN INHIBITORY PEPTIDE

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DYNAMIN INHIBITORY PEPTIDE

Product Name: DYNAMIN INHIBITORY PEPTIDE
CAS No.: 251634-21-6
Chemical Name: DYNAMIN INHIBITORY PEPTIDE
Synonyms: P4;QVPSRPNRAP;Dynamin inhibitory p;DYNAMIN INHIBITORY PEPTIDE;L-Proline, L-glutaminyl-L-valyl-L-prolyl-L-seryl-L-arginyl-L-prolyl-L-asparaginyl-L-arginyl-L-alanyl-
CBNumber: CB9687611
Molecular Formula: C47H80N18O14
Formula Weight: 1121.25
MOL File: 251634-21-6.mol

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DYNAMIN INHIBITORY PEPTIDE Property

storage temp.: Desiccate at -20°C
solubility: ≥112.1 mg/mL in DMSO; ≥23.6 mg/mL in EtOH; ≥9.4 mg/mL in H2O
form: solid
color: White to off-white
Water Solubility: Soluble to 1 mg/ml in water

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1774
Product name: Dynamininhibitorypeptide
Packaging: 1
Price: $292
Updated: 2021/12/16

ApexBio Technology

Product number: A1046
Product name: Dynamininhibitorypeptide
Packaging: 5mg
Price: $360
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0004472
Product name: DYNAMIN INHIBITORY PEPTIDE
Purity: 95.00%
Packaging: 5MG
Price: $504.12
Updated: 2021/12/16

ApexBio Technology

Product number: A1046
Product name: Dynamininhibitorypeptide
Packaging: 10mg
Price: $600
Updated: 2021/12/16

ApexBio Technology

Product number: A1046
Product name: Dynamininhibitorypeptide
Packaging: 25mg
Price: $840
Updated: 2021/12/16

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DYNAMIN INHIBITORY PEPTIDE Chemical Properties,Usage,Production

Biological Activity

dynamin inhibitory peptide is a peptide (gln-val-pro-ser-arg-pro-asn-arg-ala-pro) inhibitor of the gtpase dynamin.dynamin is a 100-kda large gtpase that functions to tabulate membranes and liberate nascent vesicles from the golgi apparatus and plasma membrane. dynamin also plays a role in many processes including division of organelles,cytokinesis and microbial pathogen resistance.dynamin inhibitory peptide competitively blocks binding of dynamin to amphiphysin thus prevents endocytosis when administered intracellularly. reduces gabaa receptor internalization and increases miniature ispc amplitude and frequency in neurons expressing gabaa receptors.figure1 formula of dynamin inhibitory peptide

storage

Store at -20°C

References

1. McNiven, M. A., Cao, H., Pitts, K. R. & Yoon, Y. (2000) Trends Biochem. Sci. 25, 115–120.2. Hinshaw, J. E. (2000) Annu. Rev. Cell Dev. Biol 16, 483–519.3. Thoms S, Erdmann R (Oct 2005). "Dynamin-related proteins and Pex11 proteins in peroxisome division and proliferation.". FEBS J 272 (20): 5169–81.4. Grabs et al (1997) The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence. J.Biol.Chem. 272 13419-25.5. Kittler et al (2000) Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J.Neurosci. 20 7972-7. 6. Nong et al (2003) Glycine binding primes NMDA receptor internalization. Nature 422 302-7.

DYNAMIN INHIBITORY PEPTIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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251634-21-6, DYNAMIN INHIBITORY PEPTIDERelated Search:

1-N-PROPOXY-2-AMINO-4-NITROBENZENE DYNAMIN INHIBITORY PEPTIDE, MYRISTOYLATED Dynamin inhibitory peptide, myristoylated (control) DYNAMIN INHIBITORY PEPTIDE

DYNAMIN INHIBITORY PEPTIDE

L-Proline, L-glutaminyl-L-valyl-L-prolyl-L-seryl-L-arginyl-L-prolyl-L-asparaginyl-L-arginyl-L-alanyl-

Dynamin inhibitory p

QVPSRPNRAP

251634-21-6

C47H80N18O14

CancerBiology

G-Protein