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AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-HIS-GLY-OH

Product Name
AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-HIS-GLY-OH
CAS No.
106128-98-7
Chemical Name
AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-HIS-GLY-OH
Synonyms
AC-ASQKRPSQRHG;MBP (1-11) HUMAN;ACETYL-MBP (135-145) (HUMAN);AC-MBP (HUMAN, PORCINE, RAT 1-11);MYELIN BASIC PROTEIN (135-145), HUMAN;ACETYL-GOLLI-MBP1 HOG7 (135-145) (HUMAN);ACETYL-MYELIN A1 PROTEIN (135-145) (HUMAN);Acetyl-Myelin Basic Protein (135-145)) (hu;MBP (1-11), GUINEA PIG, PORCINE, RABBIT, RAT;ACETYL-MYELIN BASIC PROTEIN (135-145) (HUMAN)
CBNumber
CB9688340
Molecular Formula
C52H88N22O17
Formula Weight
1293.39
MOL File
106128-98-7.mol
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AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-HIS-GLY-OH Property

Density 
1.59±0.1 g/cm3(Predicted)
pka
3.19±0.10(Predicted)
form 
Solid
Water Solubility 
Soluble in water
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
PEP0002444
Product name
MBP (1 - 11), GUINEA PIG, PORCINE, RABBIT, RAT, MYELIN BASIC PROTEIN (135 - 145), HUMAN
Purity
95.00%
Packaging
1MG
Price
$745.85
Updated
2021/12/16
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AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-HIS-GLY-OH Chemical Properties,Usage,Production

Uses

Myelin Basic Protein (1-11) is an encephalitogenic epitope of myelin basic protein (MBP). Myelin Basic Protein (1-11) can be used for induction of experimental autoimmune encephalomyelitis (EAE)[1][2].

in vivo

Myelin Basic Protein (1-11) (100 μg/mL)-pulsed DC cells (i.p.) leads to experimental autoimmune encephalomyelitis (EAE) when transferred into irradiated B10.PL mice[1].
Myelin Basic Protein (1-11) (100 μg, i.p.) induced tolerance to MBP in adult mice and prevents MBP-induced EAE[2].

References

[1] Dittel BN, et al. Presentation of the self antigen myelin basic protein by dendritic cells leads to experimental autoimmune encephalomyelitis. J Immunol. 1999 Jul 1;163(1):32-9. PMID:10384096
[2] Gaur A, et al. Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy. Science. 1992 Nov 27;258(5087):1491-4. DOI:10.1126/science.1279812

AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-HIS-GLY-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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106128-98-7, AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-HIS-GLY-OHRelated Search:


  • AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-HIS-GLY
  • MBP (1-11), guinea pig, porcine, rabbit, rat, Myelin Basic Protein (135-145), human
  • AC-MBP (HUMAN, PORCINE, RAT 1-11)
  • AC-ALA-SER-GLN-LYS-ARG-PRO-SER-GLN-ARG-HIS-GLY-OH
  • AC-ASQKRPSQRHG
  • ACETYL-GOLLI-MBP1 HOG7 (135-145) (HUMAN)
  • Acetyl-Myelin Basic Protein (135-145) (huMan) Acetyl-Golli-MBP1 HOG7 (135-145) (huMan), Acetyl-MBP (135-145) (huMan), Acetyl-Myelin A1 Protein (135-145) (huMan), Myelin Basic Protein (1-11) (guinea pig, horse, porcine, rabbit, rat)
  • Acetyl-Golli-MBP1 HOG7 (135-145) (huMan), Acetyl-MBP (135-145) (huMan), Acetyl-Myelin A1 Protein (135-145) (huMan), Myelin Basic Protein (1-11) (guinea pig, horse, porcine, rabbit, rat)
  • MYELIN BASIC PROTEIN (1-11) (GUINEA PIG, HORSE, PORCINE, RABBIT, RAT)
  • MYELIN BASIC PROTEIN (135-145), HUMAN
  • ACETYL-MYELIN A1 PROTEIN (135-145) (HUMAN)
  • ACETYL-MYELIN BASIC PROTEIN (135-145) (HUMAN)
  • ACETYL-MYELIN BASIC PROTEIN (HUMAN, RAT, 1-11)
  • ACETYL-MBP (135-145) (HUMAN)
  • MBP (1-11), GUINEA PIG, PORCINE, RABBIT, RAT
  • MBP (1-11) HUMAN
  • Glycine, N-acetyl-L-alanyl-L-seryl-L-glutaminyl-L-lysyl-L-arginyl-L-prolyl-L-seryl-L-glutaminyl-L-arginyl-L-histidyl-
  • 235:PN:WO2010033207 SEQID:291 claimed protein
  • Acetyl-Myelin Basic Protein (135-145)) (hu
  • Acetyl-Myelin Basic Protein (Human, Porcine, Rat, 1-11)
  • Acetyl-Myelin Basic Protein (135-145) (huMan) Acet
  • 106128-98-7
  • Peptide