3-Quinuclidinol
- Product Name
- 3-Quinuclidinol
- CAS No.
- 1619-34-7
- Chemical Name
- 3-Quinuclidinol
- Synonyms
- QUINUCLIDIN-3-OL;Quinuclidinol;3-HYDROXYQUINUCLIDINE;Quinuclidine-3-ol;BENC-002;NSC 93905;Quinuclidinol-3;3-QUINUCLIDINOL;3-Quinuclidonol;3-HydroxyquinucL
- CBNumber
- CB9694138
- Molecular Formula
- C7H13NO
- Formula Weight
- 127.18
- MOL File
- 1619-34-7.mol
3-Quinuclidinol Property
- Melting point:
- 220-223 °C(lit.)
- Boiling point:
- 235.98°C (rough estimate)
- Density
- 1.0083 (rough estimate)
- refractive index
- 1.4790 (estimate)
- storage temp.
- 2-8°C
- solubility
- Aqueous Acidic (Slightly), Chloroform (Sparingly), Methanol (Slightly)
- form
- Crystalline Powder
- pka
- 14.75±0.20(Predicted)
- color
- White to beige
- Water Solubility
- soluble
- Sensitive
- Air Sensitive
- Merck
- 14,8082
- BRN
- 104327
- LogP
- 0.17
- CAS DataBase Reference
- 1619-34-7(CAS DataBase Reference)
- NIST Chemistry Reference
- 3-Quinuclidinol(1619-34-7)
- EPA Substance Registry System
- 1-Azabicyclo[2.2.2]octan-3-ol (1619-34-7)
Safety
- Hazard Codes
- C,F
- Risk Statements
- 34-11
- Safety Statements
- 26-36/37/39-45-16
- RIDADR
- UN 3263 8/PG 2
- WGK Germany
- 3
- RTECS
- VD6191700
- F
- 34
- Hazard Note
- Corrosive
- TSCA
- Yes
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29333920
- Hazardous Substances Data
- 1619-34-7(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
N-Bromosuccinimide Price
- Product number
- 253340
- Product name
- 3-Quinuclidinol
- Purity
- 99%
- Packaging
- 5g
- Price
- $57.9
- Updated
- 2023/06/20
- Product number
- 253340
- Product name
- 3-Quinuclidinol
- Purity
- 99%
- Packaging
- 25g
- Price
- $141
- Updated
- 2023/06/20
- Product number
- B21503
- Product name
- 3-Quinuclidinol, 98+%
- Packaging
- 5g
- Price
- $37.6
- Updated
- 2023/06/20
- Product number
- B21503
- Product name
- 3-Quinuclidinol, 98+%
- Packaging
- 25g
- Price
- $118
- Updated
- 2023/06/20
- Product number
- B21503
- Product name
- 3-Quinuclidinol, 98+%
- Packaging
- 100g
- Price
- $347
- Updated
- 2023/06/20
3-Quinuclidinol Chemical Properties,Usage,Production
Chemical Properties
Crystalline Solid
Uses
Hypotensive. Synthon for preparation of cholinergic receptor ligands and anesthetics
Uses
3-Quinuclidinol acts as a chiral building block for various antimuscarinic agents and other active pharmaceutical ingredients. It serves as a catalyst for condensation of methyl vinyl ketone with aldehydes. It is also used as a reagent for cleavage of beta-keto and vinylogous beta-keto esters. Further, it plays an important role as a synthon in the preparation of cholinergic receptor ligands and anesthetics. In addition to this, it is used in chemoselective alfa-iodination of acrylic esters through Morita-Baylis-Hillman reaction.
Definition
ChEBI: Quinuclidine in which a hydrogen atom at position 3 is substituted by a hydroxy group.
Hazard
Mutation.