L-Cysteine hydrochloride monohydrate Property

Melting point:

175°C

alpha 

+6.0～+7.5゜ (20℃/D)(c=8,6mol/l HCl)(calculated on the dried basis)

Density 

1.54 g/cm3

vapor pressure 

<0.1 hPa (20 °C)

refractive index 

6 ° (C=8, 1mol/L HCl)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

H₂O: 1 M at 20 °C, clear, colorless

form 

Solid

color 

White

PH Range

1 - 2

PH

0.8-1.2 (100g/l, H2O, 20℃)

optical activity

[α]20/D +5.6±0.3°, c = 5% in 5 M HCl

Water Solubility 

Soluble in cold water.

Sensitive 

Hygroscopic

λmax

λ: 260 nm Amax: 1.0
λ: 280 nm Amax: 0.3

Merck 

14,2781

BRN 

5158059

Stability:

Stable. Incompatible with strong oxidizing agents, most common metals, hydrogen chloride.

LogP

0.235 (est)

CAS DataBase Reference

7048-04-6(CAS DataBase Reference)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

HA2285000

F 

3-10-23

TSCA 

Yes

HS Code 

29309013

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

L-Cysteine hydrochloride monohydrate Chemical Properties,Usage,Production

Application

L-cysteine ​​hydrochloride monohydrate has been used in protocols to isolate dorsal root ganglion neurons (DRG).  It was also used in research to test its effect as an inhibitor of enzymatic browning of apples.

General descriptio

L-cysteine ​​hydrochloride monohydrate (LCHCMH) is a water-soluble salt of the non-essential amino acid L-cysteine. It is widely used in the pharmaceutical industry. The thermodynamic characteristics of LCHCMH in aqueous solution have been reported. [1] It can be crystallized in an orthogonal system with the P212121 space group. Its nonlinear optical (NLO) characteristics have been studied in single crystals grown by unidirectional Sankaranarayanan-Ramasamy (SR) technology.

Chemical Properties

white crystalline powder

Uses

L-Cysteine hydrochloride monohydrate has been used as a component of yeast dropout media for culturing yeasts. It has also been used as a component of differential reinforced clostridial broth (DRCM) for the isolation of clostridia.

Uses

L-Cysteine is a non-essential amino acid that can be synthesized by the human body under normal physiological conditions if a sufficient quantity of methionine is available. L-Cysteine is commonly use d as a precursor in the food and pharmaceutical industries. L-Cysteine is used as a processing aid for baking, as an additive in cigarettes, as well as in the preparation of meat flavours.

Uses

L-Cysteine hydrochloride monohydrate is used as a precursor in food, pharmaceutical and personal care products. It is actively involved in the production of flavors such as meat flavor obtained by reacting with sugars. It plays an important role as a key raw material for the manufacture of N-acetyl-L-cysteine, S-carboxymethyl-L-cysteine and L-cysteine base. It is involved in the treatment of liver disease as an antioxidant and antidote. Being an essential amino acid, it used as animal feed especially for sheep, which is responsible the growth of wool.

Definition

ChEBI: A hydrate that is the monohydrate form of L-cysteine hydrochloride.

General Description

This product is supplied from Wacker FERMOPURE^? material, but is sold for R&D use only, not for drug, household or other uses.

Biochem/physiol Actions

NMDA glutamatergic receptor antagonist.

Purification Methods

Likely impurities are cystine and tyrosine. Crystallise the salt from MeOH by adding diethyl ether, or from hot 20% HCl. Dry it under vacuum over P2O5. Hygroscopic. [Beilstein 4 III 1580, 1600.]