ChemicalBook > CAS DataBase List > 3-(4-NITROPHENYL)PROPANOIC ACID

3-(4-NITROPHENYL)PROPANOIC ACID

Product Name
3-(4-NITROPHENYL)PROPANOIC ACID
CAS No.
10572-16-4
Chemical Name
3-(4-NITROPHENYL)PROPANOIC ACID
Synonyms
TIMTEC-BB SBB007969;3-(P-NITROPHENOXY)PROPIONIC;3-(4-nitrophenoxy)propanoate;3-(4-NITROPHENYL)PROPIONIC ACID;3-(P-NITROPHENOXY)PROPIONIC ACID;3-(4-NITROPHENOXY)PROPIONIC ACID;3-(4-Nitrophenyloxy)propionic acid;Propanoic acid, 3-(4-nitrophenoxy)-;3-(4-NITROPHENOXY)PROPIONIC ACID ---POWDER PURE---;3-(4-NITROPHENOXY)PROPIONIC ACID ---POWDER, 98% PURE---
CBNumber
CB9708567
Molecular Formula
C9H9NO5
Formula Weight
211.17
MOL File
10572-16-4.mol
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3-(4-NITROPHENYL)PROPANOIC ACID Property

Melting point:
118-119 °C
Boiling point:
383.6±17.0 °C(Predicted)
Density 
1.380±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
4.00±0.10(Predicted)
Appearance
Light brown to brown Solid
CAS DataBase Reference
10572-16-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Hazard Note 
Irritant
HS Code 
2918999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
N900745
Product name
3-(4-Nitrophenoxy)propionicAcid
Packaging
25mg
Price
$45
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0022334
Product name
3-(4-NITROPHENOXY)PROPIONIC ACID
Purity
95.00%
Packaging
1G
Price
$692.46
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0022334
Product name
3-(4-NITROPHENOXY)PROPIONIC ACID
Purity
95.00%
Packaging
2.5G
Price
$932.6
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0022334
Product name
3-(4-NITROPHENOXY)PROPIONIC ACID
Purity
95.00%
Packaging
5G
Price
$1114.58
Updated
2021/12/16
Apolloscientific
Product number
OR10128
Product name
3-(4-Nitrophenoxy)propionic acid
Packaging
1g
Price
$57
Updated
2021/12/16
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3-(4-NITROPHENYL)PROPANOIC ACID Chemical Properties,Usage,Production

Synthesis

107-94-8

100-02-7

10572-16-4

To a 500 mL three-necked flask was added 4-nitrophenol (15 g, 108 mmol), 3-chloropropionic acid (11.6 g, 108 mmol), an aqueous ethanol solution (150 mL) and a 20% aqueous potassium hydroxide solution (150 mL). The reaction mixture was heated to reflux for 6 hours. After completion of the reaction, the mixture was cooled to room temperature and the pH was adjusted to 1-3 with dilute hydrochloric acid. the reaction mixture was extracted with ethyl acetate (300 mL x 3), the organic phases were combined and washed with saturated aqueous sodium chloride solution (300 mL x 2). The organic phase was dried over anhydrous sodium sulfate, filtered and concentrated. The crude product was purified by silica gel column chromatography (eluent: ethyl acetate/petroleum ether=1:4, v/v) to afford 3-(4-nitrophenoxy)propionic acid (8.8 g, yield 38.6%) as a white solid.

References

[1] Patent: CN108440404, 2018, A. Location in patent: Paragraph 0075; 0076; 0077; 0078
[2] Patent: WO2005/37830, 2005, A1. Location in patent: Page/Page column 18
[3] Patent: WO2012/119559, 2012, A1. Location in patent: Page/Page column 96-97
[4] Patent: WO2014/418, 2014, A1. Location in patent: Page/Page column 96; 97
[5] Patent: US2015/197511, 2015, A1. Location in patent: Paragraph 0448; 0449

3-(4-NITROPHENYL)PROPANOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-(4-NITROPHENYL)PROPANOIC ACID manufacturers

Career Henan Chemical Co
Product
3-(4-NITROPHENYL)PROPANOIC ACID 10572-16-4
Price
US $2.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
ask
Release date
2020-01-08

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