GESTONORONE CAPROATE
- Product Name
- GESTONORONE CAPROATE
- CAS No.
- 1253-28-7
- Chemical Name
- GESTONORONE CAPROATE
- Synonyms
- SH 582;ZK 5623;Depostat;SH 80582;SM-80582;NSC 84054;Primostat;Depostat (TN);Gestronol caproate;Gestronol hexanoate
- CBNumber
- CB9718151
- Molecular Formula
- C26H38O4
- Formula Weight
- 414.58
- MOL File
- 1253-28-7.mol
GESTONORONE CAPROATE Property
- Melting point:
- 123-124°
- alpha
- D +13° (chloroform)
- Boiling point:
- 453.43°C (rough estimate)
- Density
- 1.11
- refractive index
- 1.4840 (estimate)
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
- form
- Solid
- color
- Off-White to Pale Beige
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H362May cause harm to breast-fed children
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P263Avoid contact during pregnancy/while nursing.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P281Use personal protective equipment as required.
P308+P313IF exposed or concerned: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 164282
- Product name
- Gestonorone Capronate
- Packaging
- 500mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- API0011567
- Product name
- GESTONORONE CAPROATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.89
- Updated
- 2021/12/16
GESTONORONE CAPROATE Chemical Properties,Usage,Production
Originator
Depostat,Schering AG
Uses
Gestonorone Capronate, is a pro-drug of Gestonorone, which is a steroidal progestin. It has been shown to have accelerated body weight gain and caused the atrophy of the prostate, uterus, and seminal vesicles in rats. It is also an inhibitor of the reductive pathway of Testosterone (T155000) metabolism.
Uses
Gestonorone Caproate, is a pro-drug of Gestonorone, which is a steroidal progestin. It has been shown to have accelerated body weight gain and caused the atrophy of the prostate, uterus, and seminal vesicles in rats. It is also an inhibitor of the reductive pathway of Testosterone (T155000) metabolism.
Definition
ChEBI: Gestonorone caproate is an organic molecular entity.
Manufacturing Process
2 Methods of producing of 17-α-hydroxyl-19-norprogesteron-17-capronate:
1. To a solution of 1.0 g 17-α-hydroxy-19-norprogesteron in 32 ml capronic
acid anhydride 1.32 g p-toluesulfonate (1 mole hydrate) were added, and
allowed to stand for 3 h at 37°C. To the solution 1.43 ml conc. hydrochloric
acid in 143 ml methanol were added and all this also for 1 h was left under
N2. Then mixture was washed with water and treated with ether. Ether extract
was washed with water, and dried with Na2SO4. After that ether was distilled
and residue was recrystallised with isopropyl ether. 1.1 g of 17-α-hydroxyl-19-
norprogesteron-17-capronate was obtained, melting point 123°-124°C.
2. 2.0 g 3-methoxy-17α-hydroxy-17β-acetyl-δ2,5(10)-oestradien, 60 ml
capronic acid anhydride, 2.6 g p-toluensulfonate and 18.0 g water were mixed
and left for 6 h at room temperature. Then solution obtained was treated
ether and sodium bicarbonate and washed with water. Etheral solution was
dried over sodium sulfate. After distillation of ether 3.1 g 3,17α-dihydroxy-
δ3,5-19-norpregnadien-3,17-dicapronate was produced.
To solution of 3.1 g 3,17α-dihydroxy-δ3,5-19-norpregnadien-3,17-dicapronate
in 250 ml methanol 2.5 g conc. hydrochloric acid were added and mixture was
left for 1 h. Then mixture was filtered and residue was washed. After
recrystallisation with isopropyl ether 17-α-hydroxyl-19-norprogesteron-17-
capronate was obtained, melting point 121°-123°C.
Therapeutic Function
Progestin
GESTONORONE CAPROATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from GESTONORONE CAPROATE manufacturers
- Product
- GESTONORONE CAPROATE 1253-28-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-06-11