9-L-Leucine-1-9-kallidin

Product Name: 9-L-Leucine-1-9-kallidin
CAS No.: 71800-37-8
Chemical Name: 9-L-Leucine-1-9-kallidin
Synonyms: 9-L-Leucine-1-9-kallidin;(DES-ARG10,LEU9)-KALLIDIN;1-9-Kallidin, 9-L-leucine-;LYS-(DES-ARG9,LEU8)-BRADYKININ;Lys-(Des-Arg?,Leu?)-Bradykinin;[LYS0, DES-ARG9, LEU8]BRADYKININ;LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-LEU;H-LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-LEU-OH;LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-LEU: KRPPGFSPL;Lys-(Des-Arg9,Leu8)-Bradykinin (Des-Arg10,Leu9)-Kallidin
CBNumber: CB9723689
Molecular Formula: C47H75N13O11
Formula Weight: 998.2
MOL File: 71800-37-8.mol

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9-L-Leucine-1-9-kallidin Property

Density: 1.45±0.1 g/cm3(Predicted)
storage temp.: −20°C
form: Solid
pka: 3.71±0.21(Predicted)
color: White to off-white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Alfa Aesar

Product number: J66538
Product name: Lys-[Des-Arg<sup>9</sup>, Leu<sup>8</sup>]-Bradykinin
Packaging: 5mg
Price: $184
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb372521
Product name: Lys-(Des-Arg9, Leu8)-Bradykinin
Purity: > 95%
Packaging: 1mg
Price: $287.3
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb372521
Product name: Lys-(Des-Arg9, Leu8)-Bradykinin
Purity: > 95%
Packaging: 5mg
Price: $552.5
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb372521
Product name: Lys-(Des-Arg9, Leu8)-Bradykinin
Purity: > 95%
Packaging: 10mg
Price: $708.9
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: SHG0000145
Product name: LYS-(DES-ARG9, LEU8)-BRADYKININ TRIFLUOROACETATE SALT
Purity: 95.00%
Packaging: 25MG
Price: $840.44
Updated: 2021/12/16

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9-L-Leucine-1-9-kallidin Chemical Properties,Usage,Production

Description

Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt is a peptide chain containing nine amino acids. The amino acid sequence of bradykinin is Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg (RPPGFSPFR). Bradykinin is a peptide that causes blood vessels to dilate, thus resulting in lower blood pressure. A class of drugs used to lower blood pressure called ACE inhibitors lower blood pressure by increasing the concentration of bradykinin (by inhibiting its degradation). Bradykinin acts on blood vessels by releasing prostacyclin, nitric oxide, and endothelial-derived hyperpolarizing factors.

Application

As one of the end effectors of the kallikrein-kinin system,Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt has various biological activities, such as vasodilator, increase vascular permeability, induce contraction of non-vascular smooth muscle and so on.

Mechanism of action

Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt is a potent endothelium-dependent vasodilator that causes non-vascular smooth muscle contraction, increases vascular permeability and is also involved in pain mechanisms. Bradykinin also causes an increase in urine sodium, which helps lower blood pressure.

It increases calcium levels inside neocortical astrocytes, causing them to release glutamate.

In some patients treated with angiotensin I-converting enzyme (ACE) inhibitors, bradykinin has been implicated as a cause of dry cough. This difficult-to-treat cough usually results from discontinuation of ACE inhibitor therapy. In such cases, angiotensin II receptor antagonists are used as the next step in therapy.

9-L-Leucine-1-9-kallidin Preparation Products And Raw materials

Raw materials

Preparation Products

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9-L-Leucine-1-9-kallidin Suppliers

China 65 France 1 Switzerland 1 Ukraine 1 United States 4 Global 72

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Cellmano Biotech Limited

Tel: 0551-65326643 18156095617
Fax: 0551-65326641
Email: info@cellmano.com
Country: China
ProdList: 1011
Advantage: 55

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4727
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Creative Peptides

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Email: info@creative-peptides.com
Country: United States
ProdList: 6083
Advantage: 56

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27313
Advantage: 60

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29785
Advantage: 68

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973186 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 18338
Advantage: 68

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View Lastest Price from 9-L-Leucine-1-9-kallidin manufacturers

Career Henan Chemical Co

Product: (DES-ARG10,LEU9)-KALLIDIN 71800-37-8
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-18

71800-37-8, 9-L-Leucine-1-9-kallidinRelated Search:

Bisoprolol GLY-PHE-SER KALLIDIN [DES-ARG10-LEU9] KALLIDIN [3,4-PROLYL-3,4-3H(N)]- 9-L-Leucine-1-9-kallidin H-ALA-PRO-LEU-OH H-PRO-LEU-OH ARG-PRO-PRO-GLY-PHE-SER-PRO-LEU

(DES-ARG10,LEU9)-KALLIDIN

H-LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-LEU-OH

LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-LEU

LYS-(DES-ARG9,LEU8)-BRADYKININ

[LYS0, DES-ARG9, LEU8]BRADYKININ

Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt

LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-LEU: KRPPGFSPL

Lys-(Des-Arg9,Leu8)-Bradykinin (Des-Arg10,Leu9)-Kallidin

1-9-Kallidin, 9-L-leucine-

Lys-(Des-Arg9,Leu8)-Bradykinin trifluoroacetate salt H-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu-OH trifluoroacetate salt

9-L-Leucine-1-9-kallidin

Lys-(Des-Arg?,Leu?)-Bradykinin

71800-37-8

C47H75N13O11