ChemicalBook > CAS DataBase List > SUC-LEU-TYR-AMC

SUC-LEU-TYR-AMC

Product Name
SUC-LEU-TYR-AMC
CAS No.
94367-20-1
Chemical Name
SUC-LEU-TYR-AMC
Synonyms
SUC-LY-AMC;SUC-LEU-TYR-AMC;CALPAIN SUBSTRATE I;SUCCINYL-LEU-TYR-AMC;SUC-LEU-TYR-AMC USP/EP/BP;CALPAIN SUBSTRATE II, FLUOROGENIC;methyl(4-tert-butylphenoxy)acetate;SUC-LEU-TYR-7-AMINO-4-METHYLCOUMARIN;N-SUCCINYL-LEU-TYR 7-AMIDO-4-METHYLCOUMARIN;N-SUCCINYL-LEU-TYR 4-METHYLCOUMARYL-7-AMIDE
CBNumber
CB9726372
Molecular Formula
C29H33N3O8
Formula Weight
551.59
MOL File
94367-20-1.mol
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SUC-LEU-TYR-AMC Property

storage temp. 
-20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
form 
Off-white solid
color 
off-white
Sequence
{Suc}-Leu-Tyr-{AMC}
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S1153
Product name
N-Succinyl-Leu-Tyr-7-amido-4-methylcoumarin
Purity
calpain substrate
Packaging
5mg
Price
$109
Updated
2025/07/31
Sigma-Aldrich
Product number
S1153
Product name
N-Succinyl-Leu-Tyr-7-amido-4-methylcoumarin
Purity
calpain substrate
Packaging
10mg
Price
$182
Updated
2025/07/31
Cayman Chemical
Product number
10008120
Product name
Suc-Leu-Tyr-AMC
Purity
≥98%
Packaging
5mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
10008120
Product name
Suc-Leu-Tyr-AMC
Purity
≥98%
Packaging
10mg
Price
$62
Updated
2024/03/01
Sigma-Aldrich
Product number
208731
Product name
Calpain Substrate II, Fluorogenic - CAS 94367-20-1 - Calbiochem
Packaging
25mg
Price
$284
Updated
2025/07/31
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SUC-LEU-TYR-AMC Chemical Properties,Usage,Production

Uses

Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain that is used to measure the peptidase activity of the 20S proteasome.

Definition

ChEBI: Coumarin carrying a methyl group at C-4 and a succinyl-leucyl-tryrosyl side-chain at C-7.

Biological Activity

Cell permeable: no', 'Primary Target
Calpain -1 and -2', 'Product does not compete with ATP.', 'Reversible: no

SUC-LEU-TYR-AMC Preparation Products And Raw materials

Raw materials

Preparation Products

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SUC-LEU-TYR-AMC Suppliers

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94367-20-1, SUC-LEU-TYR-AMCRelated Search:


  • SUCCINYL-LEU-TYR-AMC
  • SUC-LEU-TYR-7-AMINO-4-METHYLCOUMARIN
  • SUC-LEU-TYR-AMC
  • SUC-LY-AMC
  • N-SUCCINYL-LEU-TYR 4-METHYLCOUMARYL-7-AMIDE
  • N-SUCCINYL-LEU-TYR 7-AMIDO-4-METHYLCOUMARIN
  • succinyl-leucyl-tyrosyl-4-methyl-7-coumarylamide
  • CALPAIN SUBSTRATE I
  • CALPAIN SUBSTRATE II, FLUOROGENIC
  • Calpain Substrate II, Fluorogenic - CAS 94367-20-1 - Calbiochem
  • L-Tyrosinamide, N-(3-carboxy-1-oxopropyl)-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
  • SUC-LEU-TYR-AMC USP/EP/BP
  • methyl(4-tert-butylphenoxy)acetate
  • 94367-20-1
  • C29H33N3O8
  • BioChemical
  • Biochemicals and Reagents
  • Apoptosis Products
  • Application Index
  • Calpain
  • Cell Signaling Enzymes
  • Enzymes, Inhibitors, and Substrates
  • Fluorimetric Substrates
  • peptide
  • CalpainApoptosis Enzymes
  • CalpainEnzyme Substrates
  • Fluorimetric SubstratesProteasome, Calpain and Lysosomal Proteases
  • Calpain
  • Enzyme Substrates
  • Protease Substrates
  • Substrates
  • Substrates by Enzyme