ChemicalBook > CAS DataBase List > ETHYL 2-(3-OXO-2-PIPERAZINYL)ACETATE

ETHYL 2-(3-OXO-2-PIPERAZINYL)ACETATE

Product Name
ETHYL 2-(3-OXO-2-PIPERAZINYL)ACETATE
CAS No.
33422-35-4
Chemical Name
ETHYL 2-(3-OXO-2-PIPERAZINYL)ACETATE
Synonyms
AKOS BBB/039;AKOS BC-0605;BUTTPARK 32\06-70;TIMTEC-BB SBB010112;ETHYL 3-OXOPIPERAZINE-2-ACETATE;ETHYL (3-OXOPIPERAZIN-2-YL)ACETATE;ethyl (3-oxo-2-piperazinyl)acetate;ETHYL 2-(3-OXOPIPERAZIN-2-YL)ACETATE;ETHYL 2-(3-OXO-2-PIPERAZINYL)ACETATE;ethyl 2-(3-oxopiperazin-2-yl)ethanoate
CBNumber
CB9729520
Molecular Formula
C8H14N2O3
Formula Weight
186.21
MOL File
33422-35-4.mol
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ETHYL 2-(3-OXO-2-PIPERAZINYL)ACETATE Property

Melting point:
110-111°C
Boiling point:
360.6±27.0 °C(Predicted)
Density 
1.101±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
pka
15.06±0.40(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C8H14N2O3/c1-2-13-7(11)5-6-8(12)10-4-3-9-6/h6,9H,2-5H2,1H3,(H,10,12)
InChIKey
HNYRNJAZRKCHSC-UHFFFAOYSA-N
SMILES
N1CCNC(=O)C1CC(OCC)=O
CAS DataBase Reference
33422-35-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
HazardClass 
IRRITANT
HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H304May be fatal if swallowed and enters airways

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P331Do NOT induce vomiting.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R639087
Product name
ETHYL (3-OXO-2-PIPERAZINYL)ACETATE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$30.7
Updated
2025/07/31
Sigma-Aldrich
Product number
R639087
Product name
ETHYL (3-OXO-2-PIPERAZINYL)ACETATE
Purity
AldrichCPR
Packaging
25MG
Price
$29.8
Updated
2024/03/01
TRC
Product number
E925390
Product name
Ethyl2-(3-oxo-2-piperazinyl)acetate
Packaging
2.5g
Price
$360
Updated
2021/12/16
AK Scientific
Product number
J53876
Product name
Ethyl2-(3-oxo-2-piperazinyl)acetate
Packaging
25g
Price
$414
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0029509
Product name
ETHYL 2-(3-OXO-2-PIPERAZINYL)ACETATE
Purity
95.00%
Packaging
1G
Price
$648.81
Updated
2021/12/16
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ETHYL 2-(3-OXO-2-PIPERAZINYL)ACETATE Chemical Properties,Usage,Production

Synthesis

107-15-3

141-05-9

33422-35-4

1. Ethylenediamine (1.17 mL, 17.42 mmol) and diethyl maleate (3 g, 17.42 mmol) were added to a 50 mL round bottom flask and dissolved in propanol (30 mL). 2. The reaction mixture was stirred at 55 °C for 16 h. 3. Upon completion of the reaction, the solvent was removed under reduced pressure by rotary evaporator. 4. The residue was placed in a vacuum drying chamber and The residue was dried to give the crude ethyl 2-(3-oxopiperazin-2-yl)acetate. 5. The crude product was used directly in the next step of the reaction without further purification. Yield: 3.4 g (quantitative yield).

References

[1] Patent: US2008/312231, 2008, A1. Location in patent: Page/Page column 40
[2] Journal of Heterocyclic Chemistry, 1993, vol. 30, # 1, p. 275 - 276
[3] Journal of Pharmaceutical Sciences, 1990, vol. 79, # 5, p. 447 - 452

ETHYL 2-(3-OXO-2-PIPERAZINYL)ACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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ETHYL 2-(3-OXO-2-PIPERAZINYL)ACETATE Suppliers

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View Lastest Price from ETHYL 2-(3-OXO-2-PIPERAZINYL)ACETATE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
ETHYL 2-(3-OXO-2-PIPERAZINYL)ACETATE 33422-35-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-01

33422-35-4, ETHYL 2-(3-OXO-2-PIPERAZINYL)ACETATERelated Search:

ETHYL 2-(3-OXO-2-PIPERAZINYL)ACETATE Ethyl acetate ETHYL 2-[1-(2,4-DICHLOROBENZOYL)-3-OXO-2-PIPERAZINYL]ACETATE ETHYL 2-(3-OXO-1-[(2,4,5-TRICHLOROPHENYL)SULFONYL]-2-PIPERAZINYL)ACETATE ETHYL 2-[1-(4-CHLOROBENZOYL)-3-OXO-2-PIPERAZINYL]ACETATE ETHYL 2-(1-BENZOYL-3-OXO-2-PIPERAZINYL)ACETATE ETHYL 2-[1-(2,4-DIFLUOROBENZOYL)-3-OXO-2-PIPERAZINYL]ACETATE ETHYL 2-(3-OXO-1-[3-(TRIFLUOROMETHYL)BENZOYL]-2-PIPERAZINYL)ACETATE ETHYL 2-(1-[(4-METHYLPHENYL)SULFONYL]-3-OXO-2-PIPERAZINYL)ACETATE ETHYL 2-[1-(4-METHYLBENZOYL)-3-OXO-2-PIPERAZINYL]ACETATE ETHYL 2-(1-[(3,4-DICHLOROPHENYL)SULFONYL]-3-OXO-2-PIPERAZINYL)ACETATE ETHYL 2-(1-[(4-METHOXYPHENYL)SULFONYL]-3-OXO-2-PIPERAZINYL)ACETATE ETHYL 2-[3-OXO-1-(PHENYLSULFONYL)-2-PIPERAZINYL]ACETATE ETHYL 2-[1-(3,4-DICHLOROBENZOYL)-3-OXO-2-PIPERAZINYL]ACETATE ETHYL 2-(1-[(4-BROMOPHENYL)SULFONYL]-3-OXO-2-PIPERAZINYL)ACETATE ETHYL 2-(3-OXO-1-([3-(TRIFLUOROMETHYL)PHENYL]SULFONYL)-2-PIPERAZINYL)ACETATE ETHYL 2-[1-(2,6-DICHLOROBENZOYL)-3-OXO-2-PIPERAZINYL]ACETATE ETHYL 2-[1-(2,6-DIFLUOROBENZOYL)-3-OXO-2-PIPERAZINYL]ACETATE

  • TIMTEC-BB SBB010112
  • ETHYL 3-OXOPIPERAZINE-2-ACETATE
  • ETHYL 2-(3-OXO-2-PIPERAZINYL)ACETATE
  • ETHYL 2-(3-OXOPIPERAZIN-2-YL)ACETATE
  • ETHYL (3-OXOPIPERAZIN-2-YL)ACETATE
  • BUTTPARK 32\06-70
  • (3-OXO-PIPERAZIN-2-YL)-ACETIC ACID ETHYL ESTER
  • AKOS BC-0605
  • AKOS BBB/039
  • 3-Oxo-2-piperazineacetic acid ethyl ester
  • 2-Piperazineacetic acid, 3-oxo-, ethyl ester
  • 2-(3-ketopiperazin-2-yl)acetic acid ethyl ester
  • 2-(3-oxo-2-piperazinyl)acetic acid ethyl ester
  • ethyl 2-(3-oxopiperazin-2-yl)ethanoate
  • 2-[(2R)-3-oxo-2-piperazin-1-iumyl]acetic acid ethyl ester
  • ethyl (3-oxo-2-piperazinyl)acetate
  • Ethyl 2-(3-oxopiperazin-2-yl)acetate - [E4049]
  • 33422-35-4
  • pharmacetical
  • Esters
  • Pyrans, Piperidines &Piperazines
  • CHIRAL CHEMICALS
  • Pyrans, Piperidines & Piperazines