ChemicalBook > CAS DataBase List > 4'-Methylbiphenyl-2-carboxylic acid

4'-Methylbiphenyl-2-carboxylic acid

Product Name
4'-Methylbiphenyl-2-carboxylic acid
CAS No.
7148-03-0
Chemical Name
4'-Methylbiphenyl-2-carboxylic acid
Synonyms
2-(4-METHYLPHENYL)BENZOIC ACID;AKOS BAR-0260;RARECHEM AL BO 0764;o-Tolylbenzoic acid;4′-Methyl-2-biphenyl;2-(P-TOLYL)BENZOIC ACID;Telmisartan Impurity 32;4'-Methyl-2-carboxybiphenyl;2-(p-Tolyl)benzoic Acid;2-(4-mehtylphenyl)benzoic acid
CBNumber
CB9739200
Molecular Formula
C14H12O2
Formula Weight
212.24
MOL File
7148-03-0.mol
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4'-Methylbiphenyl-2-carboxylic acid Property

Melting point:
146-148°C
Boiling point:
354.5±11.0 °C(Predicted)
Density 
1.156±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO, Methanol
form 
Solid
pka
3.90±0.36(Predicted)
color 
White
InChI
InChI=1S/C14H12O2/c1-10-6-8-11(9-7-10)12-4-2-3-5-13(12)14(15)16/h2-9H,1H3,(H,15,16)
InChIKey
ZSTUEICKYWFYIC-UHFFFAOYSA-N
SMILES
C1(C2=CC=C(C)C=C2)=CC=CC=C1C(O)=O
CAS DataBase Reference
7148-03-0(CAS DataBase Reference)
EPA Substance Registry System
[1,1'-Biphenyl]-2-carboxylic acid, 4'-methyl- (7148-03-0)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
TSCA listed
HS Code 
29163990
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
459550
Product name
4′-Methyl-2-biphenylcarboxylic acid
Purity
97%
Packaging
1g
Price
$80
Updated
2023/01/07
TCI Chemical
Product number
T2377
Product name
2-(p-Tolyl)benzoic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$17
Updated
2025/07/31
TCI Chemical
Product number
T2377
Product name
2-(p-Tolyl)benzoic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$50
Updated
2025/07/31
TRC
Product number
M294120
Product name
4’-Methylbiphenyl-2-carboxylicAcid
Packaging
2.5g
Price
$110
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM1053102
Product name
4'-METHYL BIPHENYL-2-CARBOXYLIC ACID
Purity
95.00%
Packaging
1G
Price
$128.1
Updated
2021/12/16
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4'-Methylbiphenyl-2-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Light yellow solid

Uses

4’-Methylbiphenyl-2-carboxylic Acid is used in the synthesis of angiotensin II receptor antagonists used as potent orally active antihypertensives.

General Description

4′-Methyl-2-biphenylcarboxylic acid (4′-Methyl-bi-phenyl-2-carboxyl-ic acid) can be synthesized by reacting 4′-methylbiphenyl-2-carbonitrile with methanol and 30% NaOH solution. Its crystal structure has been characterized by the centrosymmetric hydrogen-bonded dimers.

Purification Methods

Crystallise the acid from toluene or *C6H6 (m 147-148o). [Beilstein 9 H 677, 9 IV 2523.]

4'-Methylbiphenyl-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4'-Methylbiphenyl-2-carboxylic acid Suppliers

Wuhan penglei Biotechnology Co., Ltd
Tel
15871464247 17307245989
Email
3471278124@qq.com
Country
China
ProdList
4995
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
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61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
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Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
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66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
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Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9309
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66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9888
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59
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View Lastest Price from 4'-Methylbiphenyl-2-carboxylic acid manufacturers

Baoji Guokang Healthchem Co., Ltd.
Product
4'-Methylbiphenyl-2-carboxylic acid 7148-03-0
Price
US $92.00/KG
Min. Order
100KG
Purity
98%
Supply Ability
1-150mt
Release date
2021-06-08
Zhuozhou Wenxi import and Export Co., Ltd
Product
4"-Methylbiphenyl-2-carboxylic acid 7148-03-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
4"-Methylbiphenyl-2-carboxylic acid 7148-03-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

7148-03-0, 4'-Methylbiphenyl-2-carboxylic acidRelated Search:


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  • 7148-03-0
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  • CH3C6H4C6H4CO2H
  • Organic Building Blocks
  • Carboxylic Acids
  • Carbonyl Compounds
  • C13 to C42+
  • Building Blocks
  • Organic acids
  • Hypertension
  • Biphenyl & Diphenyl ether
  • INTERMEDIATESOF
  • C13 to C42+
  • Carbonyl Compounds
  • Carboxylic Acids
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts