ChemicalBook > CAS DataBase List > 20-CARBOXY-LEUKOTRIENE B4

20-CARBOXY-LEUKOTRIENE B4

Product Name
20-CARBOXY-LEUKOTRIENE B4
CAS No.
80434-82-8
Chemical Name
20-CARBOXY-LEUKOTRIENE B4
Synonyms
20-COOH-LTB4;20-CARBOXY-LEUKOTRIENE B4;20-hydroxy-20-oxoleukotriene B4;5S,12R-DIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENE-1,20-DIOIC ACID;(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenedioic acid;6,8,10,14-Eicosatetraenedioic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12R,14Z)-
CBNumber
CB9769067
Molecular Formula
C20H30O6
Formula Weight
366.45
MOL File
80434-82-8.mol
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20-CARBOXY-LEUKOTRIENE B4 Property

Boiling point:
588.3±50.0 °C(Predicted)
Density 
1.151±0.06 g/cm3(Predicted)
Flash point:
14℃
storage temp. 
−20°C
solubility 
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
pka
4.66±0.10(Predicted)
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Safety

Hazard Codes 
F,Xi
Risk Statements 
11-36/37/38
Safety Statements 
16-26-36
RIDADR 
UN 1170 3/PG 2
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C6046
Product name
20-Carboxy-leukotriene B4
Purity
~1?mg/mL in ethanol, ≥90% (HPLC)
Packaging
25μg
Price
$428
Updated
2023/06/20
Cayman Chemical
Product number
20180
Product name
20-carboxy Leukotriene B4
Purity
≥97%
Packaging
25μg
Price
$174
Updated
2024/03/01
Cayman Chemical
Product number
20180
Product name
20-carboxy Leukotriene B4
Purity
≥97%
Packaging
50μg
Price
$328
Updated
2024/03/01
Cayman Chemical
Product number
20180
Product name
20-carboxy Leukotriene B4
Purity
≥97%
Packaging
100μg
Price
$618
Updated
2024/03/01
TRC
Product number
C724805
Product name
20-COOH-LTB4
Packaging
100μg
Price
$540
Updated
2021/12/16
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20-CARBOXY-LEUKOTRIENE B4 Chemical Properties,Usage,Production

Description

20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. The resulting 20-hydroxy LTB4 is further oxidized to 20-carboxy LTB4. LTB4 metabolism in isolated rat hepatocytes also results in production of 20-carboxy LTB4 along with other ω-oxidation products. The biological activity of 20-carboxy LTB4 is only about 2.6% compared to that of LTB4 in causing PMNL degranulation.

Uses

20-COOH-LTB4 is a leukotriene B4 metabolite and substrate for β-oxidation pathways.

Definition

ChEBI: A member of the class of leukotrienes that is leukotriene B4 in which the terminal methyl group has undergone formal oxidation to the corresponding carboxylic acid.

20-CARBOXY-LEUKOTRIENE B4 Preparation Products And Raw materials

Raw materials

Preparation Products

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20-CARBOXY-LEUKOTRIENE B4 Suppliers

China 16 France 2 Germany 1 Switzerland 1 United Kingdom 1 United States 4 Global 25
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
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Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6870
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
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11289
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58
amyjetsci
Tel
027-59626688 18771149750
Email
sales@amyjet.com
Country
China
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3004
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Shanghai Yiyan Biotechnology Co. , Ltd.
Tel
021-69985186 13611928337
Email
3427709316@qq.com
Country
China
ProdList
7984
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Shanghai Yingxin laboratory equipment Co., Ltd
Tel
021-021-59178156 15300768757
Email
359382369@qq.com
Country
China
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10678
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Shanghai Guchen Biotechnology Co., LTD
Tel
021-34675735 19147740836
Email
1986399151@qq.com
Country
China
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9849
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TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.com
Country
China
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24246
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80434-82-8, 20-CARBOXY-LEUKOTRIENE B4Related Search:

(5S,12R)-5,12,20-TRIHYDROXY-(6Z,8E,10E,14Z)-EICOSATETRAENOIC ACID LEUKOTRIENE B4 20-CARBOXY-LEUKOTRIENE B4

  • 20-CARBOXY-LEUKOTRIENE B4
  • 20-COOH-LTB4
  • 5S,12R-DIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENE-1,20-DIOIC ACID
  • (5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenedioic acid
  • 20-hydroxy-20-oxoleukotriene B4
  • 6,8,10,14-Eicosatetraenedioic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12R,14Z)-
  • 80434-82-8
  • C20H30O6
  • Leukotrienes
  • Lipids
  • Fatty Acids
  • Biochemicals and Reagents
  • BioChemical
  • Fatty Acids
  • Leukotrienes
  • Lipids