1-(Tetrahydro-2H-pyran-4-yl)ethanone
- Product Name
- 1-(Tetrahydro-2H-pyran-4-yl)ethanone
- CAS No.
- 137052-08-5
- Chemical Name
- 1-(Tetrahydro-2H-pyran-4-yl)ethanone
- Synonyms
- ACP;1-(tetrahydro-2H-pyran-4-yl)ethan-1-one;FASN2A;NDUFAB1;MGC65095;EOS-61643;1-(oxan-4-yL;1-(oxan-4-yl)ethanone;4-Acetyltetrahydropyran;1-(oxan-4-yl)ethan-1-one
- CBNumber
- CB9794612
- Molecular Formula
- C7H12O2
- Formula Weight
- 128.17
- MOL File
- 137052-08-5.mol
1-(Tetrahydro-2H-pyran-4-yl)ethanone Property
- Boiling point:
- 90-94℃/15mm
- Density
- 1.024
- refractive index
- 1.4530
- storage temp.
- -20°C
- form
- Liquid
- color
- Colorless to pale yellow
- InChI
- InChI=1S/C7H12O2/c1-6(8)7-2-4-9-5-3-7/h7H,2-5H2,1H3
- InChIKey
- VNMXIOWPBADSIC-UHFFFAOYSA-N
- SMILES
- C(=O)(C1CCOCC1)C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B416173
- Product name
- 1-(Tetrahydro-2H-pyran-4-yl)ethanone
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 2H17-1-Y6
- Product name
- 4-Acetyltetrahydro-2H-pyran
- Packaging
- 5G
- Price
- $64
- Updated
- 2021/12/16
- Product number
- OR60176
- Product name
- 4-Acetyltetrahydro-2H-pyran
- Purity
- 97%
- Packaging
- 1g
- Price
- $22
- Updated
- 2021/12/16
- Product number
- 2H17-1-Y6
- Product name
- 4-Acetyltetrahydro-2H-pyran
- Packaging
- 1g
- Price
- $24
- Updated
- 2021/12/16
- Product number
- CS-D1226
- Product name
- 1-(Tetrahydro-2H-pyran-4-yl)ethanone
- Purity
- 98.48%
- Packaging
- 5g
- Price
- $48
- Updated
- 2021/12/16
1-(Tetrahydro-2H-pyran-4-yl)ethanone Chemical Properties,Usage,Production
Uses
1-(Tetrahydro-2H-pyran-4-yl)ethanone is mainly used as an intermediate in organic synthesis and medicinal chemistry, and can be used in the synthesis of cell biology detection reagents. In organic synthetic transformations, the keto carbonyl group in 1-(Tetrahydro-2H-pyran-4-yl)ethanone can be reacted with Wittig's reagent to prepare a variety of polysubstituted olefinic compounds, and in addition, the keto carbonyl group can be reduced to a hydroxyl group by the corresponding reducing agent.
Synthesis
345216-96-8
137052-08-5
Example 1 (Synthesis of 4-acetyltetrahydropyran) In a 10 mL glass flask equipped with a stirring device, a thermometer and a reflux condenser, 0.38 g (2.0 mmol) of methyl 4-acetyltetrahydro-2H-pyran-4-carboxylate (synthesized according to the method of Reference Example 1) of 99% purity and 1.08 mL (10 mmol) of 9 mol/L sulfuric acid were added. The reaction mixture was heated to 120°C under stirring and the reaction lasted for 1.5 hours. Upon completion of the reaction, the reaction mixture was analyzed by gas chromatography (internal standard method) and the formation of 0.25 g (yield: 96%) of 4-acetyltetrahydropyran was confirmed.
References
[1] Patent: EP1700852, 2006, A1. Location in patent: Page/Page column 7-8
[2] Patent: EP1700852, 2006, A1. Location in patent: Page/Page column 8
[3] Patent: EP1700852, 2006, A1. Location in patent: Page/Page column 8
[4] Patent: EP1700852, 2006, A1. Location in patent: Page/Page column 8
[5] Patent: WO2011/50016, 2011, A1. Location in patent: Page/Page column 35-36
1-(Tetrahydro-2H-pyran-4-yl)ethanone Preparation Products And Raw materials
Raw materials
Preparation Products
1-(Tetrahydro-2H-pyran-4-yl)ethanone Suppliers
- Tel
- 028-82666846 18080826311
- Fax
- QQ 2917178106
- sales@astatech.com.cn
- Country
- China
- ProdList
- 499
- Advantage
- 58
- Tel
- 15928014948; 15928014948
- 3438599507@qq.com
- Country
- China
- ProdList
- 97
- Advantage
- 58
- Tel
- 0531-61320525 15866703830
- figo.gao@foxmail.com
- Country
- China
- ProdList
- 5178
- Advantage
- 58
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9310
- Advantage
- 66
- Tel
- 025-83697070
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 15883
- Advantage
- 64
- Tel
- +86 (21) 6435-5022
- Country
- China
- ProdList
- 4267
- Advantage
- 65
- Tel
- 18270980682
- Fax
- 021 51613951
- mlcheng@sunwaypharm.cn
- Country
- China
- ProdList
- 8669
- Advantage
- 57
- Tel
- 021-53292253
- Fax
- 021-53292253
- biz@synches.com
- Country
- China
- ProdList
- 199
- Advantage
- 64
- Tel
- 021-56491756 13512199871
- Fax
- 021-5649-1756
- 2819742715@qq.com
- Country
- China
- ProdList
- 4000
- Advantage
- 55
View Lastest Price from 1-(Tetrahydro-2H-pyran-4-yl)ethanone manufacturers
- Product
- 1-(Tetrahydro-2H-pyran-4-yl)ethanone 137052-08-5
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97%min
- Supply Ability
- 30tons/month
- Release date
- 2023-02-22
- Product
- 1-(Tetrahydro-2H-pyran-4-yl)ethanone 137052-08-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2023-03-27
- Product
- 1-(Tetrahydro-2h-pyran-4-yl)ethanone 137052-08-5
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99.5%
- Supply Ability
- 100 tons
- Release date
- 2022-01-26