ChemicalBook > CAS DataBase List > 1-(Tetrahydro-2H-pyran-4-yl)ethanone

1-(Tetrahydro-2H-pyran-4-yl)ethanone

Product Name
1-(Tetrahydro-2H-pyran-4-yl)ethanone
CAS No.
137052-08-5
Chemical Name
1-(Tetrahydro-2H-pyran-4-yl)ethanone
Synonyms
ACP;1-(tetrahydro-2H-pyran-4-yl)ethan-1-one;FASN2A;NDUFAB1;MGC65095;EOS-61643;1-(oxan-4-yL;1-(oxan-4-yl)ethanone;4-Acetyltetrahydropyran;1-(oxan-4-yl)ethan-1-one
CBNumber
CB9794612
Molecular Formula
C7H12O2
Formula Weight
128.17
MOL File
137052-08-5.mol
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1-(Tetrahydro-2H-pyran-4-yl)ethanone Property

Boiling point:
90-94℃/15mm
Density 
1.024
refractive index 
1.4530
storage temp. 
-20°C
form 
Liquid
color 
Colorless to pale yellow
InChI
InChI=1S/C7H12O2/c1-6(8)7-2-4-9-5-3-7/h7H,2-5H2,1H3
InChIKey
VNMXIOWPBADSIC-UHFFFAOYSA-N
SMILES
C(=O)(C1CCOCC1)C
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Safety

Hazard Codes 
Xn
Risk Statements 
42-36
Safety Statements 
22-45-26
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
B416173
Product name
1-(Tetrahydro-2H-pyran-4-yl)ethanone
Packaging
50mg
Price
$60
Updated
2021/12/16
SynQuest Laboratories
Product number
2H17-1-Y6
Product name
4-Acetyltetrahydro-2H-pyran
Packaging
5G
Price
$64
Updated
2021/12/16
Apolloscientific
Product number
OR60176
Product name
4-Acetyltetrahydro-2H-pyran
Purity
97%
Packaging
1g
Price
$22
Updated
2021/12/16
SynQuest Laboratories
Product number
2H17-1-Y6
Product name
4-Acetyltetrahydro-2H-pyran
Packaging
1g
Price
$24
Updated
2021/12/16
ChemScene
Product number
CS-D1226
Product name
1-(Tetrahydro-2H-pyran-4-yl)ethanone
Purity
98.48%
Packaging
5g
Price
$48
Updated
2021/12/16
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1-(Tetrahydro-2H-pyran-4-yl)ethanone Chemical Properties,Usage,Production

Uses

1-(Tetrahydro-2H-pyran-4-yl)ethanone is mainly used as an intermediate in organic synthesis and medicinal chemistry, and can be used in the synthesis of cell biology detection reagents. In organic synthetic transformations, the keto carbonyl group in 1-(Tetrahydro-2H-pyran-4-yl)ethanone can be reacted with Wittig's reagent to prepare a variety of polysubstituted olefinic compounds, and in addition, the keto carbonyl group can be reduced to a hydroxyl group by the corresponding reducing agent.

Synthesis

345216-96-8

137052-08-5

Example 1 (Synthesis of 4-acetyltetrahydropyran) In a 10 mL glass flask equipped with a stirring device, a thermometer and a reflux condenser, 0.38 g (2.0 mmol) of methyl 4-acetyltetrahydro-2H-pyran-4-carboxylate (synthesized according to the method of Reference Example 1) of 99% purity and 1.08 mL (10 mmol) of 9 mol/L sulfuric acid were added. The reaction mixture was heated to 120°C under stirring and the reaction lasted for 1.5 hours. Upon completion of the reaction, the reaction mixture was analyzed by gas chromatography (internal standard method) and the formation of 0.25 g (yield: 96%) of 4-acetyltetrahydropyran was confirmed.

References

[1] Patent: EP1700852, 2006, A1. Location in patent: Page/Page column 7-8
[2] Patent: EP1700852, 2006, A1. Location in patent: Page/Page column 8
[3] Patent: EP1700852, 2006, A1. Location in patent: Page/Page column 8
[4] Patent: EP1700852, 2006, A1. Location in patent: Page/Page column 8
[5] Patent: WO2011/50016, 2011, A1. Location in patent: Page/Page column 35-36

1-(Tetrahydro-2H-pyran-4-yl)ethanone Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(Tetrahydro-2H-pyran-4-yl)ethanone Suppliers

AstaTech(Chengdu) Biopharmaceutical Corp.
Tel
028-82666846 18080826311
Fax
QQ 2917178106
Email
sales@astatech.com.cn
Country
China
ProdList
499
Advantage
58
Chengdu Zhongde Jihua Pharmaceutical Technology Co., Ltd
Tel
15928014948; 15928014948
Email
3438599507@qq.com
Country
China
ProdList
97
Advantage
58
Jinan Kabotang Biological Technology Co.,Ltd.
Tel
0531-61320525 15866703830
Email
figo.gao@foxmail.com
Country
China
ProdList
5178
Advantage
58
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
Advantage
64
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Synches Co., Ltd.
Tel
021-53292253
Fax
021-53292253
Email
biz@synches.com
Country
China
ProdList
199
Advantage
64
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
4000
Advantage
55
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View Lastest Price from 1-(Tetrahydro-2H-pyran-4-yl)ethanone manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
1-(Tetrahydro-2H-pyran-4-yl)ethanone 137052-08-5
Price
US $0.00/KG
Min. Order
1KG
Purity
97%min
Supply Ability
30tons/month
Release date
2023-02-22
LY Global chemicals co.,ltd .
Product
1-(Tetrahydro-2H-pyran-4-yl)ethanone 137052-08-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2023-03-27
Honest Joy Holdings Limited
Product
1-(Tetrahydro-2h-pyran-4-yl)ethanone 137052-08-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99.5%
Supply Ability
100 tons
Release date
2022-01-26

137052-08-5, 1-(Tetrahydro-2H-pyran-4-yl)ethanoneRelated Search:


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