BAY-1797

Product Name: BAY-1797
CAS No.: 2055602-83-8
Chemical Name: BAY-1797
Synonyms: BAY-1797;Benzeneacetamide, N-[3-(aminosulfonyl)-4-(3-chlorophenoxy)phenyl]-;paw,ion,inhibit,anti-inflammatory,CFA,Complete,P2XRs,BAY-1797,Freund’s,selective,channel,P2X Receptor,inflamed,Inhibitor,BAY1797,Adjuvant,BAY 1797,P2X,anti-nociceptive
CBNumber: CB98022694
Molecular Formula: C20H17ClN2O4S
Formula Weight: 416.88
MOL File: 2055602-83-8.mol

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BAY-1797 Property

Density: 1.414±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO (>25 mg/ml)
pka: 9.84±0.60(Predicted)
form: solid
color: Pale brown
Stability:: Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0109406
Product name: BAY-1797
Purity: 98.66%
Packaging: 5mg
Price: $205
Updated: 2021/12/16

ChemScene

Product number: CS-0109406
Product name: BAY-1797
Purity: 98.66%
Packaging: 10mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0109406
Product name: BAY-1797
Purity: 98.66%
Packaging: 50mg
Price: $695
Updated: 2021/12/16

ChemScene

Product number: CS-0109406
Product name: BAY-1797
Purity: 98.66%
Packaging: 100mg
Price: $1250
Updated: 2021/12/16

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BAY-1797 Chemical Properties,Usage,Production

Description

BAY-1797 (2055602-83-8) is a selective P2X4 receptor antagonist (IC50 = 211 nM HEK cellular assay; P2X4 calcium influx based assays – hIC50 = 108 nM, mIC50 = 112 nM, rIC50 = 233 nM).1 Displayed antinociceptive and anti-inflammatory effects in mouse CFA inflammatory pain models.

storage

Store at -20°C

References

Werner et al. (2019) Discovery and Characterization of the Potent and Selective P2X4 Inhibitor N-[4-(3-Chlorophenoxy)-3-sulfamoylphenyl]-2-phenylacetamide (BAY-1797) and Structure-Guided Amelioration of Its CYP3A4 Induction Profile; J. Med. Chem. 62 11194

BAY-1797 Preparation Products And Raw materials

Raw materials

Preparation Products

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BAY-1797 Suppliers

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BAY-1797

paw,ion,inhibit,anti-inflammatory,CFA,Complete,P2XRs,BAY-1797,Freund’s,selective,channel,P2X Receptor,inflamed,Inhibitor,BAY1797,Adjuvant,BAY 1797,P2X,anti-nociceptive

Benzeneacetamide, N-[3-(aminosulfonyl)-4-(3-chlorophenoxy)phenyl]-

2055602-83-8