AMINOACETONE HYDROCHLORIDE
- Product Name
- AMINOACETONE HYDROCHLORIDE
- CAS No.
- 7737-17-9
- Chemical Name
- AMINOACETONE HYDROCHLORIDE
- Synonyms
- 1-aminopropan-2-one hydrochloride;Aminoacetone HCl;1-AMINOPROPAN-2-ONE HCL;AMINOACETONE HYDROCHLORIDE;2-OxopropylaMMoniuM Chloride;1-Aminoacetone hydrochloride, >=95%;2-Propanone, 1-aMino-, hydrochloride;1-aminopropan-2-one hydrochloride salt;2-Propanone, 1-aMino-,hydrochloride (8CI,9CI);AMINOACETONE HYDROCHLORIDE ISO 9001:2015 REACH
- CBNumber
- CB9804593
- Molecular Formula
- C3H8ClNO
- Formula Weight
- 109.55472
- MOL File
- 7737-17-9.mol
AMINOACETONE HYDROCHLORIDE Property
- Melting point:
- 73-74 °C
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- DMF: 25 mg/ml; DMSO: 15 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 10 mg/ml
- form
- A crystalline solid
- color
- Off-white to yellow
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C3H7NO.ClH/c1-3(5)2-4;/h2,4H2,1H3;1H
- InChIKey
- RUCLDQBBIJKQHO-UHFFFAOYSA-N
- SMILES
- C(=O)(C)CN.Cl
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 17573
- Product name
- Aminoacetone (hydrochloride)
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 17573
- Product name
- Aminoacetone (hydrochloride)
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $61
- Updated
- 2024/03/01
- Product number
- 17573
- Product name
- Aminoacetone (hydrochloride)
- Purity
- ≥95%
- Packaging
- 50mg
- Price
- $193
- Updated
- 2024/03/01
- Product number
- A580060
- Product name
- 1-AminoacetoneHydrochloride
- Packaging
- 50mg
- Price
- $135
- Updated
- 2021/12/16
- Product number
- FA17679
- Product name
- 1-Aminoacetone hydrochloride
- Packaging
- 5G
- Price
- $400
- Updated
- 2021/12/16
AMINOACETONE HYDROCHLORIDE Chemical Properties,Usage,Production
Description
Aminoacetone is a threonine and glycine catabolite that can be converted to methylglyoxal by amine oxidases. It has been identified as one of several endogenous sources of methylglyoxal found in the plasma of diabetes patients. As a pro-oxidant, 0.10-5 mM aminoacetone can induce cell death in RINm5f pancreatic β-cells. Aminoacetone is used as a growth substrate for Pseudomonas.
Chemical Properties
White to Off-White Solid
Uses
Aminoacetone hydrochloride is the simplest monopeptide. Aminoacetone hydrochloride is an intermediate in the metabolism of threonine and glycine. Aminoacetone hydrochloride is an endogenous substrate for semicarbazide-sensitive amine oxidase (SSAO), and can be used for determination of SSAO activity[1].
Synthesis
111491-97-5
7737-17-9
1-Benzyloxycarbonylamino-2-propanone (3) (8.6 g, 42 mmol) was used as a raw material, which was dissolved in ethanol (50 mL) and 1N hydrochloric acid solution (46 mL) was added. The reaction was stirred in the presence of Pd/C catalyst (1.5 g, 10%) for 4 h at room temperature in a hydrogen atmosphere (1 atm). Upon completion of the reaction, the reaction mixture was filtered to remove the catalyst and the filtrate was concentrated. The resulting residue was ground with ether (Et2O) to give 1-amino-2-propanone hydrochloride (4.6 g, 100%) as a white solid.1H NMR (CD3OD) data: δ 3.92 (s, 2H), 2.12 (s, 3H).
References
[1] Deng Y, et al. Assessment of the deamination of aminoacetone, an endogenous substrate for semicarbazide-sensitive amine oxidase. Anal Biochem. 1999 May 15;270(1):97-102. DOI:10.1006/abio.1999.4058
AMINOACETONE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from AMINOACETONE HYDROCHLORIDE manufacturers
- Product
- 1-Aminopropan-2-one hydrochloride 7737-17-9
- Price
- US $8.80-2.20/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-27
- Product
- AMINOACETONE HYDROCHLORIDE 7737-17-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 500kg/month
- Release date
- 2019-08-01