BI-9321

Product Name: BI-9321
CAS No.: 2387510-86-1
Chemical Name: BI-9321
Synonyms: BI-9321;BI9321,BI 9321;Benzenemethanamine, 4-[5-(7-fluoro-4-quinolinyl)-1-methyl-1H-imidazol-4-yl]-3,5-dimethyl-
CBNumber: CB98054329
Molecular Formula: C22H21FN4
Formula Weight: 360.43
MOL File: 2387510-86-1.mol

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BI-9321 Property

Boiling point:: 524.0±50.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
pka: 8.87±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 6665
Product name: BI9321
Purity: ≥98%(HPLC)
Packaging: 5
Price: $207
Updated: 2021/12/16

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BI-9321 Chemical Properties,Usage,Production

Biological Activity

BI-9321 is a potent, selective, and cellularly active NSD3-PWWP1 antagonist with a Kd of 166 nM. BI-9321 is not valid for NSD2-PWWP1 and NSD3-PWWP2. BI-9321 specifically disrupts the interaction of NSD3-PWWP1 with histones in U2OS cells with IC50 of 1.2 μM.

in vitro

BI-9321 is targeting the methyl-lysine binding site of the PWWP1 domain with sub-micromolar in vitro activity and cellular target engagement at 1 μM. As a single agent, BI-9321 downregulates Myc messenger RNA expression and reduces proliferation in MOLM-13 cells.

target

Kd: 166 nM (NSD3-PWWP1)

BI-9321 Preparation Products And Raw materials

Raw materials

Preparation Products

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BI-9321 Suppliers

China 5 United States 4 Global 9

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29774
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

Beijing Keyi Tongda Technology Development Co., Ltd

Tel: 17743531240
Email: kytd20@sina.com
Country: China
ProdList: 1514
Advantage: 58

TargetMol Chemicals Inc.

Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Country: United States
ProdList: 19881
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

2387510-86-1, BI-9321Related Search:

BI-9321

BI9321,BI 9321

Benzenemethanamine, 4-[5-(7-fluoro-4-quinolinyl)-1-methyl-1H-imidazol-4-yl]-3,5-dimethyl-

2387510-86-1