DBCO-PEG2-acid

Product Name: DBCO-PEG2-acid
CAS No.: 2304558-25-4
Chemical Name: DBCO-PEG2-acid
Synonyms: DBCO-PEG2-PA;DBCO-PEG2-COOH;DBCO-PEG2-acid
CBNumber: CB98054697
Molecular Formula: C26H28N2O6
Formula Weight: 464.51
MOL File: 2304558-25-4.mol

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DBCO-PEG2-acid Property

Boiling point:: 803.0±65.0 °C(Predicted)
Density: 1.30±0.1 g/cm3(Predicted)
storage temp.: -20°C, protect from light
solubility: Soluble in DMSO, DCM, DMF
pka: 4.28±0.10(Predicted)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-24290
Product name: DBCO-PEG2-acid
Purity: 97%
Packaging: 25mg
Price: $170
Updated: 2021/12/16

BroadPharm

Product number: BP-24290
Product name: DBCO-PEG2-acid
Purity: 97%
Packaging: 100mg
Price: $380
Updated: 2021/12/16

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DBCO-PEG2-acid Chemical Properties,Usage,Production

Description

DBCO-PEG2-acid is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain allows for increased water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

DBCO-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG2-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

DBCO-PEG2-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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DBCO-PEG2-acid Suppliers

China 25 United States 3 Global 28

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 40000
Advantage: 60

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 021-58088081 Q2635253576
Fax: QQ3382968513
Email: hailey@shsendpharm.com
Country: China
ProdList: 875
Advantage: 55

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80534353 19917294565
Email: et@chemextension.com
Country: China
ProdList: 3868
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Hunan chemfish Scientific co.,ltd

Tel: 85567275 18570329630
Email: sales06@chemfish.com
Country: China
ProdList: 4967
Advantage: 58

Alfa Chemistry

Tel: +1-5166625404;
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 20405
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32470
Advantage: 58

Henan Lien Chemical Products Co., Ltd.

Tel: 0371-63357898 15378766539
Email: 535046669@qq.com
Country: China
ProdList: 4762
Advantage: 58

Guangzhou Younan Technology Co., Ltd

Tel: 020-82000279 18988941452
Fax: QQ：3283937693
Email: YN_research@163.com
Country: China
ProdList: 3000
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 54995
Advantage: 58

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View Lastest Price from DBCO-PEG2-acid manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: DBCO-PEG2-PA 2304558-25-4
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2026-02-04

2304558-25-4, DBCO-PEG2-acidRelated Search:

DBCO-PEG2-acid

DBCO-PEG2-COOH

DBCO-PEG2-PA

2304558-25-4