ChemicalBook > CAS DataBase List > 3,3-DIMETHYLCYCLOBUTANECARBOXYLIC ACID

3,3-DIMETHYLCYCLOBUTANECARBOXYLIC ACID

Product Name
3,3-DIMETHYLCYCLOBUTANECARBOXYLIC ACID
CAS No.
34970-18-8
Chemical Name
3,3-DIMETHYLCYCLOBUTANECARBOXYLIC ACID
Synonyms
3,3-DIMETHYLCYCLOBUTANECARBOXYLIC ACID;3,3-dimethylcyclobutane-1-carboxylic acid;Cyclobutanecarboxylic acid, 3,3-dimethyl-
CBNumber
CB9805787
Molecular Formula
C7H12O2
Formula Weight
128.17
MOL File
34970-18-8.mol
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3,3-DIMETHYLCYCLOBUTANECARBOXYLIC ACID Property

Boiling point:
206℃
Density 
1.053
Flash point:
96℃
storage temp. 
Sealed in dry,Room Temperature
pka
4.82±0.40(Predicted)
form 
liquid
color 
Colourless
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Safety

Hazard Codes 
Xn
Risk Statements 
22
HS Code 
2916200090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
D460090
Product name
3,3-DimethylcyclobutanecarboxylicAcid
Packaging
500mg
Price
$175
Updated
2021/12/16
AK Scientific
Product number
4278AB
Product name
3,3-Dimethylcyclobutanecarboxylicacid
Packaging
1g
Price
$216
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD164844
Product name
3,3-Dimethylcyclobutane-1-carboxylic acid
Packaging
500mg
Price
$260
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD164844
Product name
3,3-Dimethylcyclobutane-1-carboxylic acid
Packaging
100mg
Price
$83
Updated
2021/12/16
SynQuest Laboratories
Product number
2221-1-27
Product name
3,3-Dimethylcyclobutanecarboxylic acid
Purity
97%
Packaging
250mg
Price
$93
Updated
2021/12/16
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3,3-DIMETHYLCYCLOBUTANECARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

231303-93-8

34970-18-8

The general procedure for the synthesis of 3,3-dimethylcyclobutanecarboxylic acid from the compound (CAS:231303-93-8) was as follows: intermediate 285C (250 mg, 1.452 mmol) was dissolved in pyridine (5 mL) and the reaction was stirred for 16 h at 120 °C. After completion of the reaction, the reaction mixture was cooled to room temperature and the reaction was quenched with 1.5 N HCl aqueous solution. Subsequently, extraction was carried out with ether (2 x 50 mL) at 0 °C. The organic layers were combined, washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford intermediate 285D as a viscous liquid (170 mg, 91% yield).1H NMR (400 MHz, DMSO-d6) δ ppm: 2.90-3.02 (m, 1H), 1.84-1.95 (m, 4H), 1.07-1.14 (m, 3H) , 0.99-1.07 (m, 3H).

References

[1] Patent: US9273058, 2016, B2. Location in patent: Page/Page column 329; 330; 331
[2] Tetrahedron, 1999, vol. 55, # 19, p. 6119 - 6128
[3] Tetrahedron Letters, 1990, vol. 31, # 21, p. 2975 - 2978
[4] Patent: WO2015/129926, 2015, A1. Location in patent: Page/Page column 101

3,3-DIMETHYLCYCLOBUTANECARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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3,3-DIMETHYLCYCLOBUTANECARBOXYLIC ACID Suppliers

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View Lastest Price from 3,3-DIMETHYLCYCLOBUTANECARBOXYLIC ACID manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
3,3-DIMETHYLCYCLOBUTANECARBOXYLIC ACID 34970-18-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-09
Career Henan Chemical Co
Product
3,3-DIMETHYLCYCLOBUTANECARBOXYLIC ACID 34970-18-8
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
1ton
Release date
2020-01-02